Browsing by Author "Koenig, Joyce M."

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    Stem Cells: Potential Therapy for Neonatal Injury?
    (Elsevier, 2015-09) Yoshimoto, Momoko; Koenig, Joyce M.; Department of Pediatrics, IU School of Medicine
    Stem cell transplantation (SCT) is an established first-line or adjunctive therapy for a variety of neonatal and adult diseases. New evidence in preclinical models as well as a few human studies show the potential utility of SCT in neuroprotection and in the modulation of inflammatory injury in at risk-neonates. This review briefly summarizes current understanding of human stem cell biology during ontogeny and present recent evidence supporting SCT as a viable approach for postinsult neonatal injury.