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Item Developing User Personas to Aid in the Design of a User-Centered Natural Product-Drug Interaction Information Resource for Researchers(AMIA, 2018) Boyce, Richard D.; Ragueneau-Majlessi, Isabelle; Yu, Jingjing; Tay-Sontheimer, Jessica; Kinsella, Chris; Chou, Eric; Brochhausen, Mathias; Judkins, John; Gufford, Brandon T.; Pinkleton, Bruce E.; Cooney, Rebecca; Paine, Mary F.; McCune, Jeannine S.; Medicine, School of MedicinePharmacokinetic interactions between natural products and conventional drugs can adversely impact patient outcomes. These complex interactions present unique challenges that require clear communication to researchers. We are creating a public information portal to facilitate researchers’ access to credible evidence about these interactions. As part of a user-centered design process, three types of intended researchers were surveyed: drug-drug interaction scientists, clinical pharmacists, and drug compendium editors. Of the 23 invited researchers, 17 completed the survey. The researchers suggested a number of specific requirements for a natural product-drug interaction information resource, including specific information about a given interaction, the potential to cause adverse effects, and the clinical importance. Results were used to develop user personas that provided the development team with a concise and memorable way to represent information needs of the three main researcher types and a common basis for communicating the design’s rationale.