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Browsing by Author "Kim, Seungmo"
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Item Coverage of the Gay Games from 1980-2012 in U.S. Newspapers: An Analysis of Newspaper Article Framing(2014-03) Lee, Soonhwan; Kim, Seungmo; Love, AdamMany members of the LGBT community have viewed the Gay Games as an opportunity to challenge dominant ideologies concerning sexuality and sport participation. Members of the mass media, however, play a potentially important role in how the event is perceived by the general public. Therefore, the primary purpose of the current study was to examine how the Gay Games have been framed in newspaper coverage. A total of 646 articles published in the United States covering the eight Gay Games events held during the 32-year period of 1980–2012 were analyzed in terms of three aspects of framing: (a) the types of issues highlighted, (b) the sources of information cited, and (c) the manner in which either episodic or thematic narratives were employed. The results of the current study revealed that issues of identity and optimism were most commonly highlighted, LGBT participants were most frequently cited as sources of information, and thematic framing was most commonly employed in newspaper coverage of the Gay Games.Item How does sport-related mobile apps usage motivation affect consumer perceptions of the sport organizations?(2019) Lee, Soonhwan; Kim, Seungmo; Shin, Hongbum; Wang, Suosheng; Tourism, Conventions, and Event Management, School of Physical Education and Tourism ManagementThe current study was to examine the relationship how the usage motivation features (i.e., perceived customization, involvement, and liking) of sport related mobile applications(apps) affect users' perception on sport organizations' reputation which were modified from the previous research (Guillory & Sundar, 2014). Results indicate that all the three usage motivation factors of sport related mobile apps positively influenced perceived sport organizations' reputation. Specifically, the results revealed that the higher level of customization of the mobile apps, the more positive apps users' perception of sport organization reputation. The current study could provide the implications that understanding the usage motivation factors of sport related mobile apps is crucial to foster a positive relationship between the public and sport organizations. Thus, understanding what motivation factors drives sport consumers to use of sport related mobile apps is one of the keys to successful mobile apps marketing in sport business and need to be further studied.Item Motivation factors influencing intention of mobile sports apps use by applying the unified theory of acceptance and use of technology (UTAUT)(Korea Institute of Sport Science, 2017) Lee, Soonhwan; Kim, Seungmo; Wang, Suosheng; Kinesiology, School of Health and Human SciencesThe current study was to test how the modified Unified Theory of Acceptance and Use of Technology (UTAUT) can apply to continuance intention of mobile sports apps. As a result of survey procedures and after eliminating incomplete questionnaires, a total of 267 responses (N=267) of college students who encompasses the greatest proportion of mobile technology devices users were garnered for main analysis. The results of proposed model testing indicate that social utility (i.e., information of sports), entertainment (i.e., escape from routine), and effort expectancy (i.e., easiness to use) are important factors influencing continuance intention of mobile sports apps. This proposed test of the modified UTAUTmay contribute to develop theoretical and conceptual model in sports related technology users’ motivation and satisfaction literatures. Further theoretical and managerial implications are also discussed.Item Tumor-intrinsic role of ICAM-1 in driving metastatic progression of triple-negative breast cancer through direct interaction with EGFR(Springer Nature, 2024-10-16) Kang, Jae‑Hyeok; Uddin, Nizam; Kim, Seungmo; Zhao, Yi; Yoo, Ki‑Chun; Kim, Min‑Jung; Hong, Sung‑Ah; Bae, Sangsu; Lee, Jeong‑Yeon; Shin, Incheol; Jin, Young Woo; O’Hagan, Heather M.; Yi, Joo Mi; Lee, Su‑Jae; Medical and Molecular Genetics, School of MedicineTriple-negative breast cancer (TNBC), the most aggressive subtype, presents a critical challenge due to the absence of approved targeted therapies. Hence, there is an urgent need to identify effective therapeutic targets for this condition. While epidermal growth factor receptor (EGFR) is prominently expressed in TNBC and recognized as a therapeutic target, anti-EGFR therapies have yet to gain approval for breast cancer treatment due to their associated side effects and limited efficacy. Here, we discovered that intercellular adhesion molecule-1 (ICAM-1) exhibits elevated expression levels in metastatic breast cancer and serves as a pivotal binding adaptor for EGFR activation, playing a crucial role in malignant progression. The activation of EGFR by tumor-expressed ICAM-1 initiates biased signaling within the JAK1/STAT3 pathway, consequently driving epithelial-to-mesenchymal transition and facilitating heightened metastasis without influencing tumor growth. Remarkably, ICAM-1-neutralizing antibody treatment significantly suppressed cancer metastasis in a breast cancer orthotopic xenograft mouse model. In conclusion, our identification of ICAM-1 as a novel tumor intrinsic regulator of EGFR activation offers valuable insights for the development of TNBC-specific anti-EGFR therapies.