Browsing by Author "Karyadi, Kenny A."
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Item Beliefs About the Direct Comparison of E-Cigarettes and Cigarettes(Taylor & Francis, 2017) Hershberger, Alexandra R.; Karyadi, Kenny A.; VanderVeen, J. Davis; Cyders, Melissa A.; Psychology, School of ScienceBackground: Recent data suggests that positive beliefs about electronic cigarettes (e-cigs) use can lead to later e-cig use. Considering that many advertisements claim that e-cigs are superior to cigarettes, individuals' likelihood to view e-cigs more favorably than cigarettes can also influence subsequent e-cig use; however, no studies have directly assessed such a comparison. Objectives: The present study created and validated the Comparing E-Cigarettes and Cigarettes questionnaire (CEAC), which asks individuals to directly compare e-cigs and cigarettes on a number of dimensions, in two independent samples. Methods: In sample 1 (451 undergraduates; mean age = 20.35, SD = 5.44, 72.4% female, 73.4% Caucasian) we explored the factor structure of the CEAC and in sample 2 (699 community adults collected via Amazon's Mechanical Turk; mean age = 34.04, SD = 10.9, 47.7% female, 83.3% Caucasian) we replicated the factor structure. Results: Exploratory factor analysis suggested a three-factor structure: General Benefits (α = 0.80), General Effects (α = 0.86), and Health Benefits (α = 0.88), which was replicated via confirmatory factor analysis, χ2 = 4.36; RMSEA = 0.07, 90% CI = 0.06–0.08; TLI = 0.99; CFI = 0.99, and was relatively invariant across product use and gender. Individuals reported viewing e-cigs as safer and more beneficial than cigarettes and these beliefs were higher in e-cig users. Conclusions: Future work should establish how these comparative beliefs are influenced by e-cig use and/or influence subsequent transition to and increases in e-cig use. Although e-cigs are likely less harmful than cigarettes, and thus these comparative beliefs represent that state of nature, e-cigs are not completely without risk.Item Combined expectancies of alcohol and e-cigarette use relate to higher alcohol use(Elsevier, 2016-01) Hershberger, Alexandra R.; Karyadi, Kenny A.; VanderVeen, J. Davis; Department of Psychology, School of ScienceElectronic cigarettes (e-cigs) were created to approximate the look, feel, and experience of using a cigarette. Since cigarette and alcohol use co-occur, we hypothesized that e-cig and alcohol use also co-occur, likely due to shared positive drug expectations. Using self-report data from two independent samples of community-dwelling alcohol using adults, the present study: (1) modified the Nicotine and Other Substance Interaction Expectancy Questionnaire (NOSIE) to assess expectancies of combined e-cig and alcohol use (i.e. the individuals perceived likelihood of using e-cigs and alcohol together; NOSIE-ER); and (2) examined the relationships among e-cig use, expectancies, and alcohol use across e-cig use status. In the first sample (N=692, mean age=32.6, SD=9.74, 50.7% female, 82.2% Caucasian), exploratory factor analysis suggested the presence of two factors: (1) alcohol use leads to e-cig use (Scale 1; α=0.85); and (2) e-cig use leads to alcohol use (Scale 2; α=0.91). In the second sample (N=714, mean age=34.1, SD=10.89, 47.8% female, 75.6% Caucasian), confirmatory factor analysis supported this factor structure (χ(2)=47.00, p<0.01, df=19; RMSEA=0.08, 90% CI=0.05-0.11; TLI=0.99; CFI=0.99). Compared to non e-cig users, e-cig users had significantly higher problematic alcohol use in both samples (b's=0.09 to 0.14, p's<.05). Expectancies of combined e-cig and alcohol use were significantly related to problematic alcohol use (b's=-0.92 to 0.26, p's<.05). In sum, e-cig use is related to alcohol use and expectancies of combined e-cig and alcohol use; consequently, reshaping of beliefs about needs or desires to co-use could be a prime point of intervention.Item Examination of a Short Version of the UPPS-P Impulsive Behavior Scale(Elsevier B.V., 2014-09) Cyders, Melissa A.; Littlefield, Andrew K.; Coffey, Scott; Karyadi, Kenny A.; Department of Psychology, School of ScienceThe current study examines a recently developed short version of the UPPS-P Impulsive Behavior Scale. Participants were 251 undergraduate students (59.3% male; mean age = 21.16 ( SD = 4.18); 72% Caucasian). The short version generally replicated the internal consistency (0.74 – 0.88 across subscales) and inter-scale correlations of the full UPPS-P. Moreover, the estimated loss of shared variance was small (0% – 6.4% reductions across subscales) as compared to a 66% time- savings. Structural equation modeling replicated previously supported factor structures and relationships to external outcomes using the full UPPS-P. The short UPPS-P scale should be considered a valid and reliable alternative to the full UPPS-P.Item The Interaction between Sensation Seeking and Negative Affect Lability on Alcohol Involvement(Office of the Vice Chancellor for Research, 2013-04-05) Karyadi, Kenny A.; Coskunpinar, Ayca; Dir, Allyson L.Sensation seeking has been inconsistently associated with increased alcohol involvement, suggesting that there might be moderating factors. Considering that sensation seeking has been associated with negative affect and affect lability, negative affect lability might moderate the sensation seeking-alcohol involvement association. We hypothesized that negative affect lability would enhance the effect of sensation seeking on alcohol involvement. Using a large sample of college undergraduate students (n = 734), the current study tested whether negative affect lability moderated the effect of sensation seeking on levels of (1) hazardous alcohol use and (2) alcohol related problems. The sample was 74.6% female and 72.7% Caucasian, and had a mean age of 22.22 (SD = 6.31). Affect lability was measured as anxiety and depression lability, and as anger lability. The hypothesis was tested using multiple regression and interactions were probed using simple slope analyses. Negative affect lability moderated the effect of sensation seeking on hazardous alcohol use and alcohol related problems. Sensation seeking predicted greater levels of hazardous alcohol use among participants with low levels of ADL (b = 1.19, p < .001), but this effect weakened at high levels of ADL (b = 0.11, p = .66). Similarly, the effect of sensation seeking on alcohol related problems was strongest for participants with low levels of AL (b = 1.10, p < .001), but weaker for participants with high levels of AL (b = -.17, p = .58). These findings are inconsistent with our hypothesis, and suggest that concurrent negative affect lability actually diminishes the effect of sensation seeking on hazardous alcohol use and alcohol related problems. These findings highlight the importance of considering negative affect lability among sensation seekers with problematic alcohol use.Item The Interactive Effects of Alcohol Cravings, Cue Reactivity, and Urgency on College Student Problematic Drinking.(Office of the Vice Chancellor for Research, 2014-04-11) Karyadi, Kenny A.; Cyders, Melissa A.Introduction: Alcohol cravings have been inconsistently associated with problematic drinking. Two possible moderators are cue reactivity and urgency. Individuals high on urgency might be more likely to develop reactivity to alcohol cues due to their higher rates of drinking. This reactivity might produce greater alcohol cravings and might consequently increase problematic drinking. We hypothesized that alcohol cravings would be more strongly associated with problematic drinking at higher levels of cue reactivity and urgency. Method: In a sample of college students (n = 240), the current study tested three way interactions among cue reactivity, urgency, and alcohol cravings on problematic drinking. The sample was 70.7% female and 75% Caucasian, with a mean age of 19.37 (SD = 1.65). Urgency was measured using two UPPS Impulsive Behavior subscales. Problematic drinking was measured using the AUDIT. Alcohol cravings were measured using the Obsessive Compulsive Drinking Scale. Participants were presented with alcohol pictorial cues during the study, after which their cue reactivity was assessed using the Alcohol Urge Questionnaire. Interactions were tested using multiple regression and simple slope analyses. Results: The effect of alcohol cravings on problematic drinking was significant at low negative urgency and cue reactivity (b = 5.34, p = 0.001), low negative urgency and high cue reactivity (b = 8.69, p<0.001), high negative urgency and low cue reactivity (b = 5.53, p <0.001), and high negative urgency and cue reactivity (b = 4.71, p<0.001). A similar pattern of findings was present with positive urgency, but alcohol cravings were most strongly associated with problematic drinking at low cue reactivity and high positive urgency (b = 6.56, p<0.001). Discussion: These findings clarify the inconsistent alcohol cravings-problematic drinking associations in prior studies. These findings suggest the importance of considering cue reactivity and urgency in understanding how alcohol cravings create risk for problematic drinking.Item Mechanisms Underlying the Relationship between Negative Affectivity and Problematic Alcohol Use(Office of the Vice Chancellor for Research, 2013-04-05) Coskunpinar, Ayca; Dir, Allyson L.; Karyadi, Kenny A.; Koo, ChungSeungResearch has long supported the role of negative affectivity for problematic alcohol consumption (Bechara, 2005; Dolan, 2007; Larsen, 2000; Tice & Bratslavsky, 2000; Tice, Bratslavsky, & Baumeister, 2001). However, the mechanisms that underlie how negative affective traits influence problematic alcohol use and attentional biases are not well understood. These inconsistencies can be attributed to three possible reasons: (1) research has often utilized broad measures of negative affective traits that can mask the effect of specific underlying unidimensional traits (Smith, Fischer & Fister, 2003), (2) research has tended to utilize only the valence of traits and has often failed to consider how activation of traits might predict behavioral outcomes, and (3) research has not fully incorporated other aspects of affective traits (e.g. affective lability and emotion-based rash action) that could be serving as mechanisms in predicting problematic alcohol use. The current study sought to characterize mechanisms that drive problematic alcohol use and attentional biases. Three undergraduate student studies were conducted (n = 510, 429, and 38). Negative urgency partially mediated the effects of negative affectivity (B for indirect effect = .119, CI = .09 – .16) and affect lability (B for indirect effect = .928, CI = .47 – 1.45) on problematic alcohol use. Activation level of hostility predicted increased variance in problematic alcohol consumption (R2 change = .01, β = .16, p = .02) above trait valence. Negative urgency predicted alcohol attentional biases over and above valence and activation (β = 2.23, p = .05). Negative urgency is a prime mechanism by which negative affective traits influence problematic alcohol consumption. This suggests that the relationship between negative urgency or lack of planning and problematic alcohol consumption could be driven, in part, by increases in attentional biases when cued with alcohol stimuli, although this was not directly tested in the current study.Item A Meta-Analysis of the Relationship between Trait Mindfulness and Substance Use Behaviors(Elsevier, 2014-10-01) Karyadi, Kenny A.; VanderVeen, J. Davis; Cyders, Melissa A.; Department of Psychology, School of ScienceBackground The relationship between trait mindfulness and substance use behaviors has been inconsistent across studies. The current study is a meta-analysis aimed at quantifying the magnitude of this relationship, and at determining how this relationship varies in context of (1) mindfulness facets, (2) substance type, (3) sample characteristics, and (4) substance use severity. Methods A literature search was conducted using electronic databases. The literature search yielded 303 articles, but only 39 articles met inclusion criteria to be included in this meta-analysis. The relationship was quantified as a Pearson's r correlation coefficient for all studies. Results Findings indicated a small, negative, and significant relationship between trait mindfulness and substance use behaviors (r = -0.13). This relationship varied across substance type, clinical status of the sample, and substance use severity. Although not significant, relationship sizes showed different patterns across mindfulness facets. Conclusions This meta-analysis quantified the relationship between trait mindfulness and substance use behaviors, which can be used as future effect size estimates. Findings also clarify inconsistency in previous work by indicating that the trait mindfulness-substance use behaviors relationship was more robust: (1) for alcohol use and tobacco use behaviors; (2) for problematic substance use behaviors; and (3) with inpatient clinical samples. Further work should continue to examine if acting with awareness, non-judgment, and non-reactivity mindfulness facets are more robustly associated with substance use behaviors. Failure to consider these factors, or collapsing across these factors, could explain the smaller or inconsistently reported associations across previous studies.Item Negative Urgency Mediates the Relationship between Amygdala and Orbitofrontal Cortex Activation to Negative Emotional Stimuli and General Risk-Taking(Oxford University Press, 2015-11) Cyders, Melissa A.; Dzemidzic, Mario; Eiler, William J.; Coskunpinar, Ayca; Karyadi, Kenny A.; Kareken, David A.; Department of Psychology, School of ScienceThe tendency toward impulsive behavior under emotional duress (negative and positive urgency) predicts a wide range of maladaptive risk-taking and behavioral disorders. However, it remains unclear how urgency relates to limbic system activity as induced from emotional provocation. This study used functional magnetic resonance imaging to examine the relationship between brain responses to visual emotional stimuli and urgency traits. Twenty-seven social drinkers (mean age = 25.2, 14 males) viewed negative (Neg), neutral (Neu), and positive (Pos) images during 6 fMRI scans. Brain activation was extracted from a priori limbic regions previously identified in studies of emotional provocation. The right posterior orbitofrontal cortex (OFC) and left amygdala were activated in the [Neg>Neu] contrast, whereas the left posterior OFC was activated in the [Pos>Neu] contrast. Negative urgency was related to the right lateral OFC (r = 0.43, P = 0.03) and the left amygdala (r = 0.39, P = 0.04) [Neg>Neu] activation. Negative urgency also mediated the relationship between [Neg>Neu] activation and general risk-taking (regression weights = 3.42 for right OFC and 2.75 for the left amygdala). Emotional cue-induced activation in right lateral OFC and left amygdala might relate to emotion-based risk-taking through negative urgency.Item THE NEURAL CORRELATES OF EMOTION REGULATION AND URGENCY(Office of the Vice Chancellor for Research, 2012-04-13) Karyadi, Kenny A.; Coskunpinar, Ayca; Cyders, Melissa A.Recent studies have indicated five distinct facets of impulsivity related personality traits—each differentially related to risky behaviors. These facets are: sensation seeking, positive and negative urgency, premeditation, and perseverance. Urgency, defined as a tendency to behave impulsively in face of strong emotions, has been found to be the most consistent predictor of a number of problematic risky behaviors—including problematic substance use, pathological gambling, and problematic eating behaviors. It has been theorized that this relationship between urgency and problematic risky be-haviors can be attributed to an underlying dysfunction in the ability to regu-late emotions. No studies have examined the neural correlates of the urgen-cy facets. However, prior studies have looked at the neural correlates of emotion regulation, which is an aspect of the urgency facets. The intention of this poster is to review the neural correlates of emotion regulation in or-der to elucidate the neural mechanisms underlying the urgency facets. Our review of the literature indicates that the amygdala, orbitofrontal cortex, and anterior cingulate cortex are involved in emotion regulation. Particularly, emotion regulation processes may be attributed to the independent and syn-ergistic functioning of these regions. These findings indicate that urgency and possibly other impulsivity related personality traits may have measura-ble neural correlates. Moreover, these findings also introduce the possibility of targeting neural dysfunctions in order to reduce emotionally driven impul-siveness and consequent problematic behaviors.Item Preliminary support for the role of alcohol cues in food cravings and attentional biases(Sage, 2017) Karyadi, Kenny A.; Cyders, Melissa A.; Psychology, School of ScienceThis study examined whether alcohol odors, in isolation or when combined with pictures, would influence food attentional biases and cravings. Participants’ cravings and attentional biases to food and alcohol pictures were assessed after exposure to alcohol or water odors (n = 77; mean age = 30.84 years, 51.9% female, 83.1% Caucasian). Food attentional biases were increased by alcohol odors, but food cravings were increased only by a combination of alcohol odors and food pictures. These effects were related with self-reported problematic food consumption. These findings support a research program for further examining the effect of alcohol cues on problematic food consumption.