Browsing by Author "Javaid, Waleed"

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    Multisociety statement on coronavirus disease 2019 (COVID-19) vaccination as a condition of employment for healthcare personnel
    (Cambridge University Press, 2022-01) Weber, David J.; Al-Tawfiq, Jaffar; Babcock, Hilary; Bryant, Kristina; Drees, Marci; Elshaboury, Ramy; Essick, Katharine; Fakih, Mohamad; Henderson, David; Javaid, Waleed; Juffras, Diane; Jump, Robin L. P.; Lee, Francesca; Malani, Anurag N.; Mathew, Trini; Murthy, A. Rekha; Nace, David; O'Shea, Tara; Pettigrew, Erica; Pettis, Ann Marie; Schaffzin, Joshua; Shenoy, Erica S.; Vaishampayan, Julie; Wiley, Zanthia; Wright, Sharon B.; Yokoe, Deborah; Young, Heather; Medicine, School of Medicine
    This consensus statement by the Society for Healthcare Epidemiology of America (SHEA) and the Society for Post-Acute and Long-Term Care Medicine (AMDA), the Association for Professionals in Epidemiology and Infection Control (APIC), the HIV Medicine Association (HIVMA), the Infectious Diseases Society of America (IDSA), the Pediatric Infectious Diseases Society (PIDS), and the Society of Infectious Diseases Pharmacists (SIDP) recommends that coronavirus disease 2019 (COVID-19) vaccination should be a condition of employment for all healthcare personnel in facilities in the United States. Exemptions from this policy apply to those with medical contraindications to all COVID-19 vaccines available in the United States and other exemptions as specified by federal or state law. The consensus statement also supports COVID-19 vaccination of nonemployees functioning at a healthcare facility (eg, students, contract workers, volunteers, etc).
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    NMR metabolomics of cerebrospinal fluid differentiates inflammatory diseases of the central nervous system
    (PLOS, 2018-12-17) French, Caitlin D.; Willoughby, Rodney E.; Pan, Amy; Wong, Susan J.; Foley, John F.; Wheat, L. Joseph; Fernandez, Josefina; Encarnacion, Rafael; Ondrush, Joanne M.; Fatteh, Naaz; Paez, Andres; David, Dan; Javaid, Waleed; Amzuta, Ioana G.; Neilan, Anne M.; Robbins, Gregory K.; Brunner, Andrew M.; Hu, William T.; Mishchuk, Darya O.; Slupsky, Carolyn M.; Medicine, School of Medicine
    BACKGROUND: Myriad infectious and noninfectious causes of encephalomyelitis (EM) have similar clinical manifestations, presenting serious challenges to diagnosis and treatment. Metabolomics of cerebrospinal fluid (CSF) was explored as a method of differentiating among neurological diseases causing EM using a single CSF sample. METHODOLOGY/PRINCIPAL FINDINGS: 1H NMR metabolomics was applied to CSF samples from 27 patients with a laboratory-confirmed disease, including Lyme disease or West Nile Virus meningoencephalitis, multiple sclerosis, rabies, or Histoplasma meningitis, and 25 controls. Cluster analyses distinguished samples by infection status and moderately by pathogen, with shared and differentiating metabolite patterns observed among diseases. CART analysis predicted infection status with 100% sensitivity and 93% specificity. CONCLUSIONS/SIGNIFICANCE: These preliminary results suggest the potential utility of CSF metabolomics as a rapid screening test to enhance diagnostic accuracies and improve patient outcomes.