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Browsing by Author "Jackson, Richard D."
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Item Clinical Evaluation of a Universal Adhesive in Non-Carious Cervical Lesions(2016) Rouse, Matthew A.; Platt, Jeffrey A.; Jackson, Richard D.; Carlson, Timothy J.; Matis, Bruce A.; Cook, Norman BlaineThe “total-etch” or “etch-and-rinse” systems have been the gold standard of dental bonding for decades. However, these systems are very technique-sensitive and time-consuming compared to newer “self-etch” or “self-adhesive” systems and have been implicated in cases of postoperative sensitivity. The purpose of this study was to compare the effects of two surface treatment protocols (self-etch vs. selective-etch) on the clinical performance of a universal adhesive and resin composite in Class V non-carious cervical lesions (NCCLs). Thirty-three volunteer subjects (17 male; 16 female; age range = 20 to 75 years) having at least two NCCLs were selected from patients of record at Indiana University School of Dentistry. Each subject received one resin composite restoration (Tetric EvoCeram, Ivoclar Vivadent) utilizing a self-etch (SfE) universal adhesive (Adhese Universal, Ivoclar Vivadent) with no separate enamel etching and another restoration utilizing adhesive and selective enamel etching (SelE) with 37% phosphoric acid (H3PO4). Both the adhesive and composite were placed following the manufacturer’s instructions. The two techniques were compared for differences in sensitivity, retention, marginal discoloration, marginal adaptation, and clinical acceptability at baseline and 6 months using the Cochran-Mantel-Haenszel tests for stratified, ordered categorical outcomes. Seventy-four restorations (37 SfE, 37 SelE) in 30 volunteers were evaluated at 12 months. No significant differences were found between the SfE and SelE groups for any variable at the 12-month recall (p>0.21). Retention was 100% at 12 months for both groups. Marginal adaptation was significantly worse at 12 months than at baseline for SelE (p=0.0163), but there was no difference for SfE (p=0.08). Sensitivity improved significantly from baseline to 12 months for both SelE (p=0.0113) and SfE (p=0.0128). The results obtained from this study are comparable to results observed in similar studies. Like similar studies involving self-etch adhesives in non-carious cervical lesions, our study showed no restorations lost to caries and excellent retention. The deterioration of selective-etch dentin margins was a result that differed from similar studies. A likely explanation for this finding would be the difficulty of controlling precise placement of phosphoric acid gel, causing undesired etching of dentin; this could result in suboptimal bonding to dentin. This report on 12-month data for a two-year study indicates significantly reduced sensitivity for both the SelE and SfE groups, and deterioration of SelE marginal adaptation. No decreases in retention, marginal discoloration, or clinical acceptability were observed in either group.Item The genetic susceptibility/resistance to fluorosis among different inbred mouse strains(2003) McHenry, Melissa A.K., 1971-; Everett, Eric T.; Dean, Jeffrey A.; Gonzalez-Cabezas, Carlos, 1966-; Jackson, Richard D.; Sanders, Brian J.; Stookey, George K.Fluoridation of community water supplies for the purpose of preventing dental caries remains one of the top 10 public health interventions of the last century. However, exposure (ingestion) of greater than optimal amounts of fluoride from a variety of sources has led to an increase in the prevalence of dental fluorosis. We propose that dental fluorosis represents a complex condition caused by environmental and genetic factors. Purpose: To assess the role of genetics in the pathogenesis of dental fluorosis using genetically separate inbred strains of mice. Methods: Twelve genealogically disparate strains of mice were treated with 0 ppm, 25 ppm, and 50 ppm of fluoride in their drinking water. Each mouse was given weekly dental fluorosis evaluations. After 60 days of treatment, femurs were collected for fluoride analysis. Mandibular incisors were isolated for quantitative light induced fluorescence (QLF) studies and fluoride analysis. Digital and 35 mm images were taken of all mouse incisors in order to apply and compare the Dean's Index and the modified Thylstrup and Fejerskov Index (TFI), both indices of dental fluorosis. Skeletal radiographs were taken on the euthanized mice and later examined for extra skeletal calcifications and other gross bony deformities. Results: Differences in dental fluorosis susceptibility/resistance were identified between the strains, ranging from mild, moderate, to severe dental fluorosis. Furthermore, we found clustering of strains into distinct phenotypic groups. The A/J mouse strain was highly susceptible, with a rapid onset and severe development of dental fluorosis compared with the other strains tested. The 129P3/J mouse strain was least affected with negligible dental fluorosis. From the skeletal radiographs, no gross skeletal lesions or evidence of bone dysplasia were noted. Similar body burden of fluoride, as judged from analysis of mineralized tissues, was seen in all strains despite differences in their predispositions to develop dental fluorosis. Both the Dean's and TF indices are useful for classifying the stage or severity of fluorosis in mice, and there are advantages to the use of digital images over conventional 35 mm slide images. Both indices correlate well with the amount of fluoride exposure during amelogenesis; however, these indices are not promising indicators of fluoride burden during amelogenesis. Conclusions: QLF proved to be an innovative and useful tool for the quantification of dental fluorosis. Furthermore, these observations support the role of a genetic component in the pathogenesis of fluorosis.Item Lay public’s use of a support group for general dental problems(2016) Walker, K. K.; Jackson, Richard D.; Cariology, Operative Dentistry and Dental Public Health, School of DentistryObjective: To categorize and tabulate layperson inquiries made to an Internet dental health support site to identify oral conditions and associated behaviors of concern. Methods: A retrospective tabulation of wall postings was made from an established dental health support website hosted by WebMD over a 2-year period (April 2013-April 2015). A mixed method approach of content and thematic analysis was used. Content analysis identified content of oral health concerns, while thematic analysis using grounded theory identified themes and beliefs concerning associated behaviors. Results: The presence of non-descript growths on the tongue and swelling and/or discoloration of the lips elicited the most inquires. These were often self-diagnosed as oral candidiasis, a STD or a carcinoma, provoking high levels of self-concern. Unprotected sexual activity, excessive ingestion of soft and hard beverages, smoking and overexposure to the sun were the most frequently self-reported behaviors associated with their concerns. Many questions focused upon “normal” healing, including the amount of edema and discomfort that could occur following oral surgery or other dental procedures. Information concerning alternative treatments was often solicited, and many alluded that they had not been provided sufficient information to make informed decisions prior to dental treatment. Conclusion: Laypersons have many oral health concerns particularly in relationship to the development of undiagnosed pathologies in conjunction with a history of volitional behaviors. The dental community should monitor these sites to provide advice and links to information about common oral health concerns and their possible association with detrimental behaviors. Key words: oral health, self-help groups, knowledge, health education, online, internetItem Midwestern Latino caregivers’ knowledge, attitudes and sense making of the oral health etiology, prevention and barriers that inhibit their children’s oral health: a CBPR approach(BioMed Central, 2017) Walker, Kimberly K.; Martínez-Mier, E. Angeles; Soto-Rojas, Armando E.; Jackson, Richard D.; Stelzner, Sarah M.; Galvez, Lorena C.; Smith, Gabriela J.; Acevedo, Miriam; Dandelet, Laura; Vega, Dulce; Department of Cariology and Opperative Dentistry, IU School of DentistryUsing community-based participatory research, the Health Protection Model was used to understand the cultural experiences, attitudes, knowledge and behaviors surrounding caries etiology, its prevention and barriers to accessing oral health care for children of Latino parents residing in Central Indiana.Item Oral health beliefs and behaviors of nurse and nurse practitioner students using the HU-DBI inventory: An opportunity for oral health vicarious learning(Sciedu, 2017) Walker, Kimberly K.; Jackson, Richard D.; Cariology, Operative Dentistry and Dental Public Health, School of DentistryBackground: Oral health access to care issues are resulting in curricular changes to train nursing students as oral health educators and providers. However, little data are available concerning their personal oral health beliefs/behaviors. The study purpose was to gather information from nurse and nurse practitioner students regarding their oral health beliefs and behaviors. Methods: Using the Hiroshima University Dental Behavioural Inventory (HU-DBI), survey data were gathered from nurse and nurse practitioner students as well as dental hygiene students as controls concerning their oral health beliefs and behaviors. Results: Mean HU-DBI scores were higher among nurse practitioner than nursing students, indicating more positive beliefs/behaviors, but both were lower than dental hygiene students. Both nurse and nurse practitioner students reported significantly fewer dental visits and some poorer hygiene practices than controls. Additionally, nursing students were more likely to believe that their teeth were worsening despite brushing. Conclusions: Assessment of personal oral health beliefs/behaviors should occur early in nursing education with mentoring so that optimal modeling can positively impact patients’ oral health. Oral health education opportunities within and among disciplines are discussed.