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Browsing by Author "Igega, Christele"
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Item CONTINUOUS MONITORING OF THE GALVANIC SKIN RESPONSE(Office of the Vice Chancellor for Research, 2012-04-13) Teach, Heather; Igega, Christele; Schild, John; Carpenter, JanetGalvanic Skin Response (GSR) is an objective measurement of the electrical conductance of the skin. GSR is tightly correlated with peripheral sweat rate, which in turn is associated with many clinical conditions. These conditions include, but are not limited to, menopausal “hot flashes”, diabetic hypoglycemic and hyperglycemic episodes, and various cancers. The objective quantification of GSR can be a valuable clinical tool in evaluating the effectiveness of clinical interventions for these and other conditions. Current methods of monitoring GSR are not well suited to implementation outside of the clinical setting. The goal of this research is to develop a reliable portable device for real-time ambulatory monitoring of GSR. In order to get accurate and consistent readings, electrodes must be attached to the patient with a lasting and non-irritating electrically conductive gel with suitable impedance characteristics. Development of such a device requires consideration of many physiological factors. The distribution and density of sweat glands must be considered to determine a location for the device on the body that will yield measurable GSR without interfering with the patient’s daily activities. We are in the process of evaluating the electrical impedance of electrode and gel combinations presently used in the Carpenter lab. Quantification of the frequency dependent loading profile of the electrode-gel interface will improve the measurement accuracy of the GSR. The ionic composition of sweat and the sweat rate must be evaluated to ensure that the integrity of the interface between the body and the device is maintained throughout the monitoring period. 1Department of Biomedical Engineering, Purdue School of Engineering and Technology, Indiana University-Purdue University Indianapolis, IN 46204 2Center for Enhancing Quality of Life, Indiana University School of Nursing, IUPUI, Indianapolis, IN 46204Item Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained?(2014-11) Otte, Julie L.; Carpenter, Janet S.; Manchanda, Shalini; Rand, Kevin L.; Skaar, Todd C.; Weaver, Michael T.; Chernyak, Yelena; Zhong, Xin; Igega, Christele; Landis, CarolAlthough sleep is vital to all human functioning and poor sleep is a known problem in cancer, it is unclear whether the overall prevalence of the various types of sleep disorders in cancer is known. The purpose of this systematic literature review was to evaluate if the prevalence of sleep disorders could be ascertained from the current body of literature regarding sleep in cancer. This was a critical and systematic review of peer-reviewed, English-language, original articles published from 1980 through 15 October 2013, identified using electronic search engines, a set of key words, and prespecified inclusion and exclusion criteria. Information from 254 full-text, English-language articles was abstracted onto a paper checklist by one reviewer, with a second reviewer randomly verifying 50% (k = 99%). All abstracted data were entered into an electronic database, verified for accuracy, and analyzed using descriptive statistics and frequencies in SPSS (v.20) (North Castle, NY). Studies of sleep and cancer focus on specific types of symptoms of poor sleep, and there are no published prevalence studies that focus on underlying sleep disorders. Challenging the current paradigm of the way sleep is studied in cancer could produce better clinical screening tools for use in oncology clinics leading to better triaging of patients with sleep complaints to sleep specialists, and overall improvement in sleep quality.Item Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained?(Wiley, 2015-02) Otte, Julie L.; Carpenter, Janet S.; Manchanda, Shalini; Rand, Kevin L.; Skaar, Todd C.; Weaver, Michael; Chernyak, Yelena; Zhong, Xin; Igega, Christele; Landis, CarolAlthough sleep is vital to all human functioning and poor sleep is a known problem in cancer, it is unclear whether the overall prevalence of the various types of sleep disorders in cancer is known. The purpose of this systematic literature review was to evaluate if the prevalence of sleep disorders could be ascertained from the current body of literature regarding sleep in cancer. This was a critical and systematic review of peer-reviewed, English-language, original articles published from 1980 through 15 October 2013, identified using electronic search engines, a set of key words, and prespecified inclusion and exclusion criteria. Information from 254 full-text, English-language articles was abstracted onto a paper checklist by one reviewer, with a second reviewer randomly verifying 50% (k = 99%). All abstracted data were entered into an electronic database, verified for accuracy, and analyzed using descriptive statistics and frequencies in SPSS (v.20) (North Castle, NY). Studies of sleep and cancer focus on specific types of symptoms of poor sleep, and there are no published prevalence studies that focus on underlying sleep disorders. Challenging the current paradigm of the way sleep is studied in cancer could produce better clinical screening tools for use in oncology clinics leading to better triaging of patients with sleep complaints to sleep specialists, and overall improvement in sleep quality.