Browsing by Author "Heitz, Adaline"

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    Adherence Barriers to Breast Cancer Treatment: Fragmentation of Care, Mood Disorders, and Substance Use Disorder
    (2021-03) Wells, Lindsey; Brown, Lucy; Heitz, Adaline; Newton, Erin
    Case: The patient is a premenopausal, recently divorced 40-year-old female with a history of alcohol use disorder, anxiety, and depression. She presented with a 3-month history of a palpable right sided breast mass and was found to have Stage IIB/IIIA ER+ PR+ invasive ductal carcinoma of her right breast. She successfully completed preoperative therapy followed by a right mastectomy. She subsequently had a relapse in her alcohol use disorder and since then has had inconsistent and incomplete radiation treatment. Her substance use led to the loss of her job, custody of her children, and social support. Conclusions: We identified four primary barriers to adherence to cancer treatment: fragmentation of care, major depressive disorder, generalized anxiety disorder, and substance use disorder. As a result of these mental health and systemic communication challenges, her treatment was discontinued and her care team lost her in follow-up. Clinical Significance: As many as 28% of breast cancer patients do not complete their recommended treatment, which increases risk for recurrent breast cancers. Discontinuation of and non-adherence to therapy for breast cancers are associated with increased mortality. Among breast cancer patients who have difficulty adhering to chemotherapy treatment, a common barrier is fragmentation of care. Studies have also indicated that anxiety and depression may play explanatory roles in non-adherence to breast cancer treatment. Prevalence of depression is as high as 24% among breast cancer patients. Furthermore, rates of co-occurrence of substance use disorders in cancer patients can reach up to 35%. Substance use disorders, including alcoholism, have been associated with increased rates of non-adherence and discontinuation of hormonal treatment in individuals with ER+ breast cancer diagnoses. Interventions addressing the occurrence of mental illness and fragmented cancer care are important steps in increasing adherence among these patients.
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    The Case of the Vanishing Yoni Pearl
    (2022-03) Brown, Lucy; Heitz, Adaline; Cox, Natalie; Hulsman, Luci; Christman, Megan
    Case: A 41-year-old female presented to the Emergency Department (ED) with a retained vaginal foreign body (VFB). She reported inserting a detoxifying “yoni” pearl 36 hours prior. She was unable to remove it herself. She denied fever, vaginal pain, discharge, or dysuria. A gynecologist was consulted, and the VFB was removed manually without complications. Conclusions: The authors reviewed 29 case studies and series. Overall, tampons, condoms, menstrual cups, items used for sexual gratification, and unconventional items used for barrier contraception (e.g., aerosol caps) are among the most common VFBs in premenopausal adult women. Among postmenopausal adult women, medical devices such as pessaries can be neglected in the vagina leading to retained VFB. While most cases had no contributing risk factors, associated medical and social determinants include mental health disorders, history of sexual assault, and uninsured status. This is the first documented case of a detoxifying vaginal pearl VFB. Clinical Significance: VFB is a common presentation in the United States; from 2010 to 2014, 89,160 female patients presented to the ED with a vulvar/vaginal foreign body, many requiring gynecologic or urologic consultations and invasive procedures. Although this case was without complications, VFBs can have significant morbidity. Depending on the consistency of the foreign body, VFBs can serve as a nidus for infection with subsequent sepsis, most notably toxic shock syndrome. Other serious complications of VFBs are compression of tissue, which can lead to compromise of blood flow to that region, necrosis, perforation, and fistulas (i.e., rectovaginal or vesicovaginal). Fistula formation has also been reported as a direct result of the surgical trauma from removal of the VFB. Prevention efforts should be aimed at education about what can safely be placed in the vagina, and providers should focus on dispelling misinformation surrounding vaginal detoxification and cleanliness.