Browsing by Author "Griffith-Linsley, Jackson"

Now showing 1 - 3 of 3
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    Asymptomatic Thoracic Migration of a Ventriculoperitoneal Shunt: A Case Report
    (Springer Nature, 2024-09-18) Griffith-Linsley, Jackson; Blackwell, Matthew P.; Gulizia, Dustin J.; Medicine, School of Medicine
    Hydrocephalus is often treated with CSF diversion via ventriculoperitoneal (VP) shunting. We present the unique case of a 33-year-old female with a history of infiltrating astrocytoma and consequent obstructive hydrocephalus necessitating shunt placement. She later presented with non-specific symptoms prompting shunt evaluation. Ultimately, while a cause for her symptoms was not identified, imaging revealed distal catheter migration into the pleural space. The patient remained asymptomatic during two years of follow-up without surgical intervention. This case highlights the potential for asymptomatic distal catheter migration after VP shunt placement and underscores the importance of appropriate monitoring and management once such migration is detected.
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    Autologous stem cell transplantation in adults with atypical teratoid rhabdoid tumor: a case report and review
    (Taylor & Francis, 2024) Griffith-Linsley, Jackson; Bell, William Robert; Cohen-Gadol, Aaron; Donegan, Diane; Richardson, Angela; Robertson, Michael; Shiue, Kevin; Nevel, Kathryn; Pathology and Laboratory Medicine, School of Medicine
    Aim: Atypical teratoid rhabdoid tumor (ATRT) is a rare and highly aggressive primary CNS neoplasm, predominantly observed in children. The use of autologous stem cell transplantation (ASCT) in pediatric ATRT has shown promise; however, its utility in adult ATRT remains unclear. Patients & methods: This study presents the case of an adult patient with ATRT who is in remission after ASCT and reviews the literature on ASCT in adults with ATRT. Four cases of ATRT in adults who underwent ASCT were identified, with pertinent data summarized. Results: All five patients survived longer than the historical average survival rate, four of whom had no clinical or radiographic evidence of disease at the final follow-up. Conclusion: Based on limited data, there may be a role for ASCT in the treatment of adults with ATRT.
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    Giant Actinomyces brain abscess in an immunocompetent child: A management strategy
    (Scientific Scholar, 2021-07-06) Chicoine, Nicole H.; Griffith-Linsley, Jackson; Goh, Joling; Manaloor, John J.; Raskin, Jeffrey S.; Neurological Surgery, School of Medicine
    Background: Intraparenchymal brain abscess is a collection of microbes caused by inoculation through direct extension or hematogenous spread. Although rare, intraparenchymal abscesses are potentially fatal and can be detected when patients are symptomatic due to local mass effect on adjacent neural tissue. Brain abscess treatment includes medical management with appropriate antibiotics alone or medical management in combination with surgical debridement. Treatment strategies depend on the size and location of disease, as well as the virulence of the microorganism. Similar to medical management strategies, surgical strategies among providers are not uniform, with variation in approaches from complete extirpation of the abscess, including the abscess wall, to minimally invasive stereotactic needle aspiration. In particular, for children, there are no guidelines for therapy. Case description: We report a case of giant Actinomycosis right frontal brain abscess in an immunocompetent child without risk factors. A review of the literature for the treatment of brain abscess caused very rarely by Actinomyces in children is performed. Conclusion: Successful treatment of brain access depends on organism and location. The even more uncommon giant intraparenchymal abscesses can be managed with minimal access and prolonged antibiosis, especially when slow-growing organisms are identified. Long-term follow-up should be employed to mitigate missed late failures.