Browsing by Author "Farrell, Anne G."

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    Adolescent Women with Congenital Heart Disease: Self-Reported Reproductive Health Discussions with Health Care Providers
    (Elsevier, 2022) Katz, Amy J.; Lyon, Shannon; Farrell, Anne G.; Srivastava, Nayan; Wilkinson, Tracey A.; Shew, Marcia L.; Pediatrics, School of Medicine
    Study objective: This study evaluated self-reported discussions with health care providers (HCPs) among adolescent and young adult (AYA) women with congenital heart disease (CHD). Design: Data were collected through a one-time survey of AYA women. Setting: Participants were recruited from pediatric cardiology clinics. Participants: AYA women with CHD, ages 14-21 (N = 107) INTERVENTIONS: None MAIN OUTCOME MEASURES: Questionnaires assessed adolescent characteristics and specific HCP discussions regarding transmissibility of a cardiac condition to the infant, risk of pregnancy, and hormonal contraception. Outcome measures were self-reported discussions with HCPs about these reproductive health topics. Results: Mean age was 16.8 years (SD = 2.1). Self-reported reproductive health discussions were infrequent, including discussions on transmissibility of a heart condition to their offspring (37%), risk of pregnancy to their offspring (34%), risks of pregnancy to their health (46%), and risks of hormonal contraception given their heart condition (21%). Reported discussions were most commonly with a cardiologist. Conclusions: AYA women with CHD reported limited discussions about reproductive health topics important to those with CHD. Lack of appropriate and timely counseling could lead to poor maternal and child health outcomes. Targeted interventions that improve reproductive health discussions between HCPs and AYA women with CHD are needed to close critical information and service gaps.
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    The Effects of Progestin-Only Hormone Treatment on QT Interval in the Adolescent Female
    (Elsevier, 2021-01) Kean, Adam C.; Ayers, Mark D.; Farrell, Anne G.; Kean, Kelly A.; Brooks, Patricia W.; Shew, Marcia L.; Pediatrics, School of Medicine
    We describe the effect of exogenous progestin on the corrected QT interval (QTc) in adolescent females. In post-menarcheal females, <18 years old, we compared QTc in milliseconds (ms) on ECG evaluations in those taking exogenous progestin vs those who are not. There were 40 controls and 21 treated participants. The age range was 10–17 years. There were no differences between the groups with regard to race, height, weight, BMI, or blood pressure. In the controls, the mean QTc was 403 ±19 milliseconds (ms) vs. 397 ±15 ms in those treated (p = 0.22). Those on progestin therapy had a shorter QTc by the same magnitude difference (six ms) as the hormonal naïve group in the adult literature. We report no adverse effects of progestin associated with QTc prolongation and a trend suggesting a decreased QTc in a population of post-menarcheal adolescent females.