Browsing by Author "Fakhry, Carole"
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Item Concerns and Needs of Patients With Head and Neck Cancer in the COVID-19 Era(Sage, 2021-07) Yan, Flora; Rauscher, Erika; Hollinger, Amanda; Caputo, Mary Ann; Ready, John; Nguyen, Shaun A.; Fakhry, Carole; Nathan, Cherie-Ann O.; Leonardis, Chris; Yearout, Danielle; Day, Terry A.; Moore, Michael G.; Otolaryngology -- Head and Neck Surgery, School of MedicineObjective: To evaluate the concerns and needs of patients and survivors of head and neck cancer (HNC) in the COVID-19 era. Study Design: Prospective cross-sectional survey. Setting: Contact lists of 5 North American HNC advocacy groups. Methods: A 14-question survey was distributed to the contact lists of 5 HNC advocacy groups evaluating patient and survivor needs and concerns related to their cancer care and COVID-19. Results: There were 171 respondents, with 75% in the posttreatment period. The most common concern was contraction of COVID-19 (49%). More patients in active treatment preferred in-person visits than those in the early (≤5 years) and late (>5) survivorship period (72% vs 61% vs 40%, P < .001). A higher percentage of late survivors preferred virtual visits (38% vs 28%, P = .001). In total, 91 (53.2%) respondents sought emotional support outside of immediate family and friends. This included cancer support groups (36.2%), the medical team (29.7%), and other sources outside of these (34.1%), including faith-based organizations and online communities. A higher proportion of women than men (62% vs 41%, P = .001) were seeking emotional support outside of immediate family and friends. Conclusions: During the early stages of the COVID-19 pandemic, patients with HNC who were actively undergoing treatment had increased need for support resources and preferred in-person provider visits. Alternatively, a higher percentage of patients >5 years from treatment preferred virtual visits. Emotional support outside of family and friends was sought out by a majority of respondents. Further research is needed to determine what support and educational resources are needed to best aid these various populations.Item Radiomics Features in Predicting Human Papillomavirus Status in Oropharyngeal Squamous Cell Carcinoma: A Systematic Review, Quality Appraisal, and Meta-Analysis(MDPI, 2024-03-29) Ansari, Golnoosh; Mirza-Aghazadeh-Attari, Mohammad; Mosier, Kristine M.; Fakhry, Carole; Yousem, David M.; Radiology and Imaging Sciences, School of MedicineWe sought to determine the diagnostic accuracy of radiomics features in predicting HPV status in oropharyngeal squamous cell carcinoma (SCC) compared to routine paraclinical measures used in clinical practice. Twenty-six articles were included in the systematic review, and thirteen were used for the meta-analysis. The overall sensitivity of the included studies was 0.78, the overall specificity was 0.76, and the overall area under the ROC curve was 0.84. The diagnostic odds ratio (DOR) equaled 12 (8, 17). Subgroup analysis showed no significant difference between radiomics features extracted from CT or MR images. Overall, the studies were of low quality in regard to radiomics quality score, although most had a low risk of bias based on the QUADAS-2 tool. Radiomics features showed good overall sensitivity and specificity in determining HPV status in OPSCC, though the low quality of the included studies poses problems for generalizability.Item The role of head and neck cancer advocacy organizations during the COVID-19 pandemic(Wiley, 2020-05-29) Yan, Flora; Rauscher, Erika; Hollinger, Amanda; Caputo, Mary Ann; Ready, John; Fakhry, Carole; Nathan, Cherie-Ann O.; Leonardis, Chris; Yearout, Danielle; Tsue, Terance T.; Day, Terry A.; Moore, Michael G.; Otolaryngology -- Head and Neck Surgery, School of MedicineItem We Survived 2020 With Patient Survivors: Presidential Address(AMA, 2020-11) Nathan, Cherie-Ann O.; Fakhry, Carole; Moore, Michael G.; Otolaryngology -- Head and Neck Surgery, School of Medicine