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Browsing by Author "Ezzeddine, Fatima M."
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Item Cardiac Resynchronisation with Conduction System Pacing(Radcliffe Medical Media, 2023-08-11) Ezzeddine, Fatima M.; Leon, Isaac G.; Cha, Yong-Mei; Medicine, School of MedicineTo date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium. Up to one-third of patients with heart failure who are eligible for cardiac resynchronisation therapy do not derive benefit from BiVP. Conduction system pacing (CSP), which includes His bundle pacing and left bundle branch area pacing, has emerged as an alternative to BiVP for cardiac resynchronisation. There is mounting evidence supporting the benefits of CSP in achieving synchronous ventricular activation and repolarisation. The aim of this review is to summarise the current options and outcomes of CSP when used for cardiac resynchronisation in patients with heart failure.Item Updates on His bundle pacing: The road more traveled lately(Elsevier, 2018) Ezzeddine, Fatima M.; Dandamudi, Gopi; Medicine, School of MedicineHis bundle pacing (HBP) has continued to evolve over the past decade and has started to become a global phenomenon. Evidence is mounting of its clinical benefits as compared to both right ventricular and left ventricular pacing. In this paper, we review recent data in support of His bundle pacing and some of the challenges facing us as we advocate its increasing role in clinical practice.