Browsing by Author "Emergency Medicine, IU School of Medicine"

Now showing 1 - 3 of 3
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    Improving Postdischarge Outcomes in Acute Heart Failure
    (Wolters Kluwer, 2018-07) Chioncel, Ovidiu; Collins, Sean P.; Ambrosy, Andrew P.; Pang, Peter S.; Antohi, Elena-Laura; Iliescu, Vlad Anton; Maggioni, Aldo P.; Butler, Javed; Mebazaa, Alexandre; Emergency Medicine, IU School of Medicine
    The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF represents a change in the natural history of the disease process(6). As patients hospitalized for HF have a bad prognosis, it is crucial to utilize hospitalization as an opportunity to: 1) assess the individual components of the cardiac substrate; 2) identify and treat comorbidities; 3) identify early, safe endpoints of therapy to facilitate timely hospital discharge and outpatient follow-up; and 4) implement and begin optimization guideline-directed medical therapies (GDMTs). As outcomes are influenced by many factors, many of which are incompletely understood, a systematic approach is proposed that should start with admission and continues through post-discharge (7).
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    Mihai Gheorghiade, MD-Life and Concepts
    (Wolters Kluwer, 2018-07) Pang, Peter S.; Collins, Sean P.; Butler, Javed; Chioncel, Ovidiu; Emergency Medicine, IU School of Medicine
    How do you capture an idea, shape it, and then bring it into the world? Of his many talents, this ability was a fundamental characteristic of Mihai Gheorghiade. A quick glance through PubMed confirms his prodigious output, likely to overwhelm any novice or even expert scholar. His contribution to heart failure, especially acute heart failure (AHF), is profound, He authored several major concepts in acute heart failure, disseminated further by his students. Most concepts remained indelibly linked to his name: Digoxin trials research(1–3), AHFS (acute heart failure syndromes) definition(4), hemodynamic congestion(5), hospitalized heart failure (HHF) (6), the vulnerable phase(7,8), neutral hemodynamic agents(9), registries(10–12) and pre-trial registries(13), the “6-axis model”(14) and then the “8-axis model”(15). His work shaped the field of AHF.
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    The Vulnerable Phase of Heart Failure
    (Wolters Kluwer, 2018-07) Gracia, Ely; Singh, Prabhjot; Collins, Sean; Chioncel, Ovidiu; Pang, Peter; Butler, Javed; Emergency Medicine, IU School of Medicine