Browsing by Author "Eckert, G."

Now showing 1 - 5 of 5
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    Mechanical environment change in root, periodontal ligament, and alveolar bone in response to two canine retraction treatment strategies
    (Wiley Blackwell (Blackwell Publishing), 2015-04) Jiang, F.; Xia, Z.; Li, S.; Eckert, G.; Chen, J.; Department of Engineering Technology, School of Engineering and Technology
    OBJECTIVE: To investigate the initial mechanical environment (ME) changes in root surface, periodontal ligament (PDL), and alveolar bone due to two treatment strategies, low or high moment-to-force ratio (M/F). SETTING AND SAMPLE POPULATION: Indiana University-Purdue University Indianapolis. Eighteen patients who underwent maxillary bilateral canine retraction. MATERIAL AND METHOD: Finite element models of the maxillary canines from the patients were built based on their cone beam computed tomography scans. For each patient, the canine on one side had a specially designed T-loop spring with the M/F higher than the other side. Four stress invariants (1st principal/dilatational/3rd principal/von Mises stress) in the tissues were calculated. The stresses were compared with the bone mineral density (BMD) changes reported previously for linking the ME change to bone modeling/remodeling activities. The correlation was tested by the mixed-model anova. RESULTS: The alveolar bone in the direction of tooth movement is primarily in tension, while the PDL is in compression; the stresses in the opposite direction have a reversed pattern. The M/F primarily affects the stress in root. Three stress invariants (1st principal/3rd principal/dilatational stress) in the tooth movement direction have moderate correlations with BMD loss. CONCLUSIONS: The stress invariants may be used to characterize what the osteocytes sense when ME changes. Their distributions in the tissues are significantly different, meaning the cells experience different stimuli. The higher bone activities along the direction of tooth movement may be related to the initial volumetric increase and decrease in the alveolar bone.
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    Meta-analysis: randomized controlled trials of 4-L polyethylene glycol and sodium phosphate solution as bowel preparation for colonoscopy
    (Wiley Blackwell (Blackwell Publishing), 2010-07) Juluri, R.; Eckert, G.; Imperiale, T. F.; Department of Medicine, IU School of Medicine
    BACKGROUND: Randomized controlled trials (RCTs) comparing polyethylene glycol (PEG) with sodium phosphate (NaP) are inconsistent. AIM: To compare the efficacy of and tolerance to PEG vs. NaP for bowel preparation. METHODS: We used MEDLINE and EMBASE to identify English-language RCTs published between 1990 and 2008 comparing 4-L PEG with two 45 mL doses of NaP in adults undergoing elective colonoscopy. We calculated the pooled odds ratios (ORs) for preparation quality and proportion of subjects completing the preparation. RESULTS: From 18 trials (n = 2792), subjects receiving NaP were more likely to have an excellent or good quality preparation than those receiving PEG (82% vs. 77%; OR = 1.43; 95% CI, 1.01-2.00). Among a subgroup of 10 trials in which prep quality was reported in greater detail, there were no differences in the proportions of excellent, good, fair or poor preparation quality. Among nine trials that assessed preparation completion rates, patients receiving NaP were more likely to complete the preparation than patients receiving 4-L PEG (3.9% vs. 9.8% respectively did not complete the preparation; OR = 0.40; CI, 0.17-0.88). CONCLUSION: Among 18 head-to-head RCTs of NaP vs. 4-L PEG, NaP was more likely to be completed and to result in an excellent or good quality preparation.
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    Molar-Incisor hypomineralization in controls vs CLP with primary or prior to secondary alveolar grafts
    (Office of the Vice Chancellor for Research, 2016-04-08) Allam, E.; Ghoneima, A.; Tholpady, S.; Eckert, G.; Klene, C.; Kula, K.
    Molar incisor hypomineralization (MIH) is a congenital defect of unknown etiology that can affect both esthetics and cariogenic susceptibility. The objective of this study was to determine whether MIH is greater in patients with cleft lip and palate (CLP) who underwent primary alveolar grafting (PAG) as compared to CLP prior to secondary alveolar grafting (SAG) and to controls. A retrospective analysis of intraoral photographs of 13 (10M:3F; 8.9 ± 1.2 yrs) CLP patients who underwent a PAG, 27 (18M:9F;10.0 ± 2.1 yrs) CLP prior to SAG, and 60 (30M:30F; 12.4 ± 1.8 yrs) controls without CLP was performed. Mantel-Haenszel chi-square tests were used to compare the three groups for differences in MIH scores and Wilcoxon Rank Sum tests were used to compare the groups for differences in average MIH scores. A 5% significance level was used for all tests. MIH scores were significantly higher for the PAG and SAG groups compared to the control group (p<0.001). The PAG group had significantly higher incisor MIH (p=0.016) than the SAG group. MIH average scores were significantly higher for the two graft groups compared to the controls (p<0.0001). The PAG group had significantly higher average MIH score and average MIH score for incisors than the SAG group (p=0.03). The results suggest that CLP patients, in general, have significantly greater MIH compared with controls and CLP with PAGs have significantly greater MIH in the incisor region than CLP waiting for SAGs. The increased severity of MIH could be related to the grafting during the time of incisor crown formation.
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    Root Canal Treatment Survival Analysis in National Dental PBRN Practices
    (Sage, 2022-10) Thyvalikakath, T.; LaPradd, M.; Siddiqui, Z.; Duncan, W. D.; Eckert, G.; Medam, J. K.; Rindal, D. B.; Jurkovich, M.; Gilbert, G. H.; National Dental PBRN Collaborative Group; Dental Public Health and Dental Informatics, School of Dentistry
    Few studies have examined the longevity of endodontically treated teeth in nonacademic clinical settings where most of the population receives its care. This study aimed to quantify the longevity of teeth treated endodontically in general dentistry practices and test the hypothesis that longevity significantly differed by the patient’s age, gender, dental insurance, geographic region, and placement of a crown and/or other restoration soon after root canal treatment (RCT). This retrospective study used deidentified data of patients who underwent RCT of permanent teeth through October 2015 in 99 general dentistry practices in the National Dental Practice-Based Research Network (Network). The data set included 46,702 patients and 71,283 RCT permanent teeth. The Kaplan–Meier (product limit) estimator was performed to estimate survival rate after the first RCT performed on a specific tooth. The Cox proportional hazards model was done to account for patient- and tooth-specific covariates. The overall median survival time was 11.1 y; 26% of RCT teeth survived beyond 20 y. Tooth type, presence of dental insurance any time during dental care, placement of crown and/or receiving a filling soon after RCT, and Network region were significant predictors of survival time (P < 0.0001). Gender and age were not statistically significant predictors in univariable analysis, but in multivariable analyses, gender was significant after accounting for other variables. This study of Network practices geographically distributed across the United States observed shorter longevity of endodontically treated permanent teeth than in previous community-based studies. Also, having a crown placed following an RCT was associated with 5.3 y longer median survival time. Teeth that received a filling soon after the RCT before the crown was placed had a median survival time of 20.1 y compared to RCT teeth with only a crown (11.4 y), only a filling (11.2 y), or no filling and no crown (6.5 y).
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    Three-dimensional airway volumes and most constricted areas in children
    (Office of the Vice Chancellor for Research, 2012-04-13) Kula, K.; Ahn, E.J.; Liu, S.; Stewart, K.; Eckert, G.; Halum, S.; Dillehay, J.; Eraso, F.; Ghoneima, A.
    Objective: The objectives of this retrospective study using cone beam computed tomography (CBCT) were to determine if there are differences in the volume of various airway segments and the most constricted area (MCA) of children with different dentoskeletal patterns. Methods: The initial CBCTs of 83 orthodontic patients (30 Angle’s Class I; 26 Class II; and 27 Class III) were collected from a private orthodontic office. Following reliability studies, various parameters of the craniofacial complex, airway volume, and MCA were measured utilizing Dolphin 3D software. Comparisons among the three dental and the skeletal malocclusion classes were performed using one-way ANOVA and Fishers Protected Least Significant. Associations of the airway volumes and the MCA with other parameters were determined using correlation coefficients, accepting p < 0.05 as significant for all tests. Results: Maxillary right sinus volume was the only airway segment showing significant difference among different dental classes. Maxillary sinus volume also correlated moderately with anterior facial height and mandibular length. No significant differences were found between the MCA and different dentoskeletal classifications. Conclusions: The only significant difference in airway parameters among the dentoskeletal classes was that the dental Class II subjects had greater right sinus volume than the other classes. Shorter anterior facial height or mandibular length could be indicators for decreased airway volume in children. Funding: IUSD Graduate Research Committee, IUPUI Three-Dimensional Imaging of the Craniofacial Complex Center, Jarabak Endowed Professorship