Browsing by Author "Burnier, Michel"

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    Cardiovascular complications in chronic kidney disease: a review from the European Renal and Cardiovascular Medicine Working Group of the European Renal Association
    (Oxford University Press, 2023) Zoccali, Carmine; Mallamaci, Francesca; Adamczak, Marcin; Bueno de Oliveira, Rodrigo; Massy, Ziad A.; Sarafidis, Pantelis; Agarwal, Rajiv; Mark, Patrick B.; Kotanko, Peter; Ferro, Charles J.; Wanner, Christoph; Burnier, Michel; Vanholder, Raymond; Wiecek, Andrzej; Medicine, School of Medicine
    Chronic kidney disease (CKD) is classified into five stages with kidney failure being the most severe stage (stage G5). CKD conveys a high risk for coronary artery disease, heart failure, arrhythmias, and sudden cardiac death. Cardiovascular complications are the most common causes of death in patients with kidney failure (stage G5) who are maintained on regular dialysis treatment. Because of the high death rate attributable to cardiovascular (CV) disease, most patients with progressive CKD die before reaching kidney failure. Classical risk factors implicated in CV disease are involved in the early stages of CKD. In intermediate and late stages, non-traditional risk factors, including iso-osmotic and non-osmotic sodium retention, volume expansion, anaemia, inflammation, malnutrition, sympathetic overactivity, mineral bone disorders, accumulation of a class of endogenous compounds called 'uremic toxins', and a variety of hormonal disorders are the main factors that accelerate the progression of CV disease in these patients. Arterial disease in CKD patients is characterized by an almost unique propensity to calcification and vascular stiffness. Left ventricular hypertrophy, a major risk factor for heart failure, occurs early in CKD and reaches a prevalence of 70-80% in patients with kidney failure. Recent clinical trials have shown the potential benefits of hypoxia-inducible factor prolyl hydroxylase inhibitors, especially as an oral agent in CKD patients. Likewise, the value of proactively administered intravenous iron for safely treating anaemia in dialysis patients has been shown. Sodium/glucose cotransporter-2 inhibitors are now fully emerged as a class of drugs that substantially reduces the risk for CV complications in patients who are already being treated with adequate doses of inhibitors of the renin-angiotensin system. Concerted efforts are being made by major scientific societies to advance basic and clinical research on CV disease in patients with CKD, a research area that remains insufficiently explored.
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    Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension
    (Wolters Kluwer, 2021) Parati, Gianfranco; Stergiou, George S.; Bilo, Grzegorz; Kollias, Anastasios; Pengo, Martino; Ochoa, Juan Eugenio; Agarwal, Rajiv; Asayama, Kei; Asmar, Roland; Burnier, Michel; De La Sierra, Alejandro; Giannattasio, Cristina; Gosse, Philippe; Head, Geoffrey; Hoshide, Satoshi; Imai, Yutaka; Kario, Kazuomi; Li, Yan; Manios, Efstathios; Mant, Jonathan; McManus, Richard J.; Mengden, Thomas; Mihailidou, Anastasia S.; Muntner, Paul; Myers, Martin; Niiranen, Teemu; Ntineri, Angeliki; O'Brien, Eoin; Octavio, José Andres; Ohkubo, Takayoshi; Omboni, Stefano; Padfield, Paul; Palatini, Paolo; Pellegrini, Dario; Postel-Vinay, Nicolas; Ramirez, Agustin J.; Sharman, James E.; Shennan, Andrew; Silva, Egle; Topouchian, Jirar; Torlasco, Camilla; Wang, Ji Guang; Weber, Michael A.; Whelton, Paul K.; White, William B.; Mancia, Giuseppe; Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension; Medicine, School of Medicine
    The present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a recent statement by the American Heart association, as well as technological developments, which have occurred over the past 20 years. The present document has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH.
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    Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension
    (Wolters Kluwer, 2021) Parati, Gianfranco; Stergiou, George S.; Bilo, Grzegorz; Kollias, Anastasios; Pengo, Martino; Ochoa, Juan Eugenio; Agarwal, Rajiv; Asayama, Kei; Asmar, Roland; Burnier, Michel; De La Sierra, Alejandro; Giannattasio, Cristina; Gosse, Philippe; Head, Geoffrey; Hoshide, Satoshi; Imai, Yutaka; Kario, Kazuomi; Li, Yan; Manios, Efstathios; Mant, Jonathan; McManus, Richard J.; Mengden, Thomas; Mihailidou, Anastasia S.; Muntner, Paul; Myers, Martin; Niiranen, Teemu; Ntineri, Angeliki; O'Brien, Eoin; Octavio, José Andres; Ohkubo, Takayoshi; Omboni, Stefano; Padfield, Paul; Palatini, Paolo; Pellegrini, Dario; Postel-Vinay, Nicolas; Ramirez, Agustin J.; Sharman, James E.; Shennan, Andrew; Silva, Egle; Topouchian, Jirar; Torlasco, Camilla; Wang, Ji Guang; Weber, Michael A.; Whelton, Paul K.; White, William B.; Mancia, Giuseppe; Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension; Medicine, School of Medicine
    The present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a recent statement by the American Heart association, as well as technological developments, which have occurred over the past 20 years. The present document has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH.