Browsing by Author "Brock, Tina Penick"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    To address emerging infections, we must invest in enduring systems: The kinetics and dynamics of health systems strengthening
    (Wiley, 2015-10) Pastakia, Sonak; Njuguna, Benson; Le, Phuoc V.; Singh, Manisha K.; Brock, Tina Penick; Department of Medicine, IU School of Medicine
    Clinical pharmacology uses foundational principles of pharmacokinetics (PK) and pharmacodynamics (PD) to address medication use spanning a continuum from molecules to the masses. In the realm of infectious diseases, PK/PD attributes are considered especially important, because subtherapeutic dosing of antibiotics has been associated with poorer clinical outcomes in patients and increased incidences of drug resistance in populations. In consideration of these PK/PD principles, we will describe the analogous relationship between health systems strengthening, including for educating healthcare providers about emerging infections, and the tenets of therapeutic drug monitoring.