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Browsing by Author "Botros, David"
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Item Eletromagnetic Detection of Mild Brain Injury: A Novel Imaging Approach to Post Concussive Syndrome(Scientific Research Publishing, 2021-11) Rizkalla, James; Botros, David; Alqahtani, Nasser; Patnala, Mounica; Salama, Paul; Perez, Felipe Pablo; Rizkalla, Maher; Medicine, School of MedicineIntroduction: Mild traumatic brain injury (mTBI) is a common injury, with nearly 3 - 4 million cases annually in the United States alone. Neuroimaging in patients with mTBI provides little benefit, and is usually not indicated as the diagnosis is primarily clinical. It is theorized that microvascular trauma to the brain may be present in mTBI, that may not be captured by routine MRI and CT scans. Electromagnetic (EM) waves may provide a more sensitive medical imaging modality to provide objective data in the diagnosis of mTBI. Methods: COMSOL simulation software was utilized to mimic the anatomy of the human skull including skin, cranium, cerebrospinal fluid (CSF), gray-matter tissue of the brain, and microvasculature within the neural tissue. The effects of penetrating EM waves were simulated using the finite element analysis software and results were generated to identify feasibility and efficacy. Frequency ranges from 7 GHz to 15 GHz were considered, with 0.6 and 1 W power applied. Results: Variations between the differing frequency levels generated different energy levels within the neural tissue-particularly when comparing normal microvasculature versus hemorrhage from microvasculature. This difference within the neural tissue was subsequently identified, via simulation, serving as a potential imaging modality for future work. Conclusion: The use of electromagnetic imaging of the brain after concussive events may play a role in future mTBI diagnosis. Utilizing the proper depth frequency and wavelength, neural tissue and microvascular trauma may be identified utilizing finite element analysis.Item Patient perception of medial patellofemoral ligament reconstruction on Instagram(Taylor & Francis, 2022-04-07) Rizkalla, James M.; Holderread, Brendan; Botros, David; Orozco, Erin; Botros, Andro; Botros, Anthony; Wilson, Philip; Ellis, Henry; Orthopaedic Surgery, School of MedicineTo date, there is limited social media evaluation of patients after medial patellofemoral ligament (MPFL) reconstruction and analysis of their perceived surgical outcome. The purpose of this study was to examine patient perceived outcomes after MPFL reconstruction via social media analysis on Instagram. A total of 486 posts containing "#MPFL" were included in the assessment. The tone of the post was examined in relation to demographic variables and the content of the post. When comparing posts containing positive vs. negative tone, those referencing rehabilitation (P < 0.0001) and activities of daily living (ADLs) (P = 0.0002) were more likely to be positive. Posts referencing surgical incision or scar (P = 0.02) or postoperative instability/dislocation (P < 0.0001) were more likely to have a negative tone. Multivariable logistic regression identified references to incision/scar (odds ratio [OR]: 0.446, P = 0.0264) and instability/dislocation (OR: 0.071, P < 0.0001) as strong negative predictors of positive tone. However, referencing rehabilitation (OR: 2.464, P = 0.0091) or ADLs (OR: 2.251, P = 0.0187) substantially increased the likelihood of a positive post tone. In conclusion, positive tone was associated with improved rehabilitation and ability to perform ADLs postoperatively. In contrast, negative tone was associated with dissatisfaction with the scar/incision, as well as postoperative patellar instability.