Browsing by Author "Al-Shammari, Haifa"

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    Clinical features and prognostic factors of intensive and non-intensive 1014 COVID-19 patients: an experience cohort from Alahsa, Saudi Arabia
    (BioMed Central, 2021-05-24) Alhumaid, Saad; Al Mutair, Abbas; Al Alawi, Zainab; Al Salman, Khulud; Al Dossary, Nourah; Omar, Ahmed; Alismail, Mossa; Al Ghazal, Ali M.; Jubarah, Mahdi Bu; Al Shaikh, Hanan; Al Mahdi, Maher M.; Alsabati, Sarah Y.; Philip, Dayas K.; Alyousef, Mohammed Y.; Al Brahim, Abdulsatar H.; Al Athan, Maitham S.; Alomran, Salamah A.; Ahmed, Hatim S.; Al-Shammari, Haifa; Elhazmi, Alyaa; Rabaan, Ali A.; Al-Tawfiq, Jaffar A.; Al-Omari, Awad; Medicine, School of Medicine
    COVID-19 is a worldwide pandemic and has placed significant demand for acute and critical care services on hospitals in many countries.
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    Clinical, epidemiological, and laboratory characteristics of mild-to-moderate COVID-19 patients in Saudi Arabia: an observational cohort study
    (BMC, 2020) Al Mutair, Abbas; Alhumaid, Saad; Alhuqbani, Waad N.; Zaidi, Abdul Rehman Z.; Alkoraisi, Safug; Al-Subaie, Maha F.; AlHindi, Alanoud M.; Abogosh, Ahmed K.; Alrasheed, Aljwhara K.; Alsharafi, Aya A.; Alhuqbani, Mohammed N.; Alhowar, Njoud A.; Salih, Samer; Alhedaithy, Mogbil A.; Al-Tawfiq, Jaffar A.; Al-Shammari, Haifa; Abdulqawi, Rayid; Ismail, Alaa F.; Hamdan, Noura; Saad, Fares; Olhaye, Fahad A.; Eltahir, Tarig A.; Rabaan, Ali A.; Al-Omari, Awad; Medicine, School of Medicine
    Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged from China in December 2019 and has presented as a substantial and serious threat to global health. We aimed to describe the clinical, epidemiological, and laboratory findings of patients in Saudi Arabia infected with SARS-CoV-2 to direct us in helping prevent and treat coronavirus disease 2019 (COVID-19) across Saudi Arabia and around the world. Materials and methods Clinical, epidemiological, laboratory, and radiological characteristics, treatment, and outcomes of pediatric and adult patients in five hospitals in Riyadh, Saudi Arabia, were surveyed in this study. Results 401 patients (mean age 38.16 ± 13.43 years) were identified to be SARS-CoV-2 positive and 80% of cases were male. 160 patients had moderate severity and 241 were mild in severity. The most common signs and symptoms at presentation were cough, fever, fatigue, and shortness of breath. Neutrophil and lymphocyte counts, aspartate aminotransferase, C-reactive protein, and ferritin were higher in the COVID-19 moderate severity patient group. Mild severity patients spent a shorter duration hospitalized and had slightly higher percentages of abnormal CT scans and X-ray imaging. Conclusions This study provides an understanding of the features of non-ICU COVID-19 patients in Saudi Arabia. Further national collaborative studies are needed to streamline screening and treatment procedures for COVID-19.
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    Five-year resistance trends in pathogens causing healthcare-associated infections at a multi-hospital healthcare system in Saudi Arabia, 2015-2019
    (Elsevier, 2021) Al Mutair, Abbas; Alhumaid, Saad; Al Alawi, Zainab; Zaidi, Abdul Rehman Z.; Alzahrani, Ahmed J.; Al-Tawfiq, Jaffar A.; Al-Shammari, Haifa; Rabaan, Ali A.; Khojah, Osamah; Al-Omari, Awad; Medicine, School of Medicine
    Objectives: Awareness of antimicrobial resistance (AMR) patterns in a given healthcare setting is important to inform the selection of appropriate antimicrobial therapy to reduce the further rise and spread of AMR as well as the rate of healthcare-associated infections (HAIs) and multidrug-resistant (MDR) organisms. We aimed to describe resistance patterns to several antimicrobial agents in pathogens causing HAIs isolated from patients using data gathered at three private tertiary-care hospitals in Saudi Arabia. Methods: Data on trends in AMR among bacteria causing HAIs and MDR events in children and adults at three private hospitals were collected retrospectively (2015-2019) using surveillance data. Results: Over the 5-year period, 29 393 pathogens caused 17 539 HAIs in 15 259 patients. Approximately 57.3% of patients were female and the mean age was 38.4 ± 16.8 years (81.4% adults, 18.6% children). Gram-negative pathogens were four times more likely to cause HAIs compared with Gram-positive bacteria (79.3% vs. 20.7%). Ranking of causative pathogens in decreasing order was Escherichia coli (42.2%), Klebsiella spp. (16.8%) and Staphylococcus aureus (13.9%). Acinetobacter spp. were the only pathogens to decrease significantly (7% reduction; P = 0.033). The most common resistant pathogens were extended-spectrum cephalosporin-resistant E. coli (37.1%), extended-spectrum cephalosporin-resistant Klebsiella (27.8%), carbapenem-non-susceptible Acinetobacter spp. (19.5%), carbapenem-non-susceptible Pseudomonas aeruginosa (19.2%) and methicillin-resistant S. aureus (18.6%). Conclusion: National collaboration is required by prompt feedback to local authorities to tackle regional differences in AMR. This can help plan timely containment interventions to stop and contain microbial threats and swiftly assess their impact.