Browsing by Author "Abdullah, Noor"

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    Adverse events and residual lesion rate after cold endoscopic mucosal resection of serrated lesions ≥10 mm
    (Elsevier, 2020) McWhinney, Connor D.; Vemulapalli, Krishna C.; El-Rahyel, Ahmed; Abdullah, Noor; Rex, Douglas K.; Medicine, School of Medicine
    Background and Aims Cold endoscopic mucosal resection (EMR) is being increasingly used for large serrated lesions. We sought to measure residual lesion rates and adverse events after cold EMR of large serrated lesions. Methods In a single academic center, we retrospectively examined a database of serrated class lesions ≥ 10 mm removed with cold EMR for safety and efficacy. Results Five hundred and sixty-six serrated lesions ≥10 mm in size were removed from 312 patients. We successfully contacted 223 patients (71.5%) with no reported serious adverse events that required hospitalization, repeat endoscopy, or transfusion. The residual lesion rate per lesion at first follow-up colonoscopy was 18 out of 225 (8%; 95% CI, 5-12.1). Lesions with residual were larger at polypectomy compared with lesions without recurrence (median, 23 mm vs 16 mm, p=0.017). Conclusion Cold EMR appears to be safe and effective for the removal of large serrated lesions.
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    Yield of a second right colon examination during colonoscopy after a first examination using a mucosal exposure device
    (Elsevier, 2022-01) Vemulapalli., Krishna C.; Lahr, Rachel E.; Lee, Christopher J.; Abdullah, Noor; Rex, Douglas K.; Medicine, School of Medicine
    Background and Aims Double right colon examination during colonoscopy has been advocated to reduce the risk of interval cancer in the right colon. Whether 2 examinations are necessary when the first examination is performed with a mucosal exposure device is uncertain. We documented the rates of missed adenomas, sessile serrated lesions, and hyperplastic polyps after an initial right colon examination by a high-level detector using a mucosal exposure device. Methods At a single tertiary hospital outpatient practice, we prospectively collected data on the yield of a second examination of the right colon after an initial examination by a single high-detecting colonoscopist using a mucosal exposure device. Results During the study period, 1331 eligible consecutive patients underwent colonoscopy. Right colon adenoma, sessile serrated lesion, and hyperplastic polyp miss rates were 15.8%, 14.1%, and 16.7%, respectively. Four percent of patients had adenomas detected in the right colon only with a second examination. Conclusions A second examination of the right colon is warranted, even when using a distal mucosal exposure device to perform colonoscopy.