Combatting ESKAPE Pathogens and Antibiotic Resistance

Abstract

Antibiotic resistance is a medical crisis that must be address within the upcoming years. Since their development in the 1930’s, people have completely relied on antibiotics to keep human populations safe from infectious disease. The CDC estimates that nearly 154 million antibiotic prescriptions are given out by doctors each year to combat dangerous diseases. However, the effectiveness of these antibiotics is at risk due to microbes rapidly adapting resistant or immunity to these treatment. Antibiotic resistance is now being acquired at a rate far faster than antibiotic development. As a result many people are dying from diseases that were once easily treated by antibiotics. To combat antibiotic resistance, soil microbes can be analysis to determine if they have the potential to combat dangerous pathogens. Microorganisms in the soil can be bacteria, actino-mycetes, viruses, fungi, algae, and protozoa; each microbe has diversity properties and characteristics. Many soil micro-organisms have produce anti-biotic compounds against pathogenic bacteria, thus these soil microbes could be used as antibiotics. In this research, microorganisms from a sample of soil were collected, isolated, and tested for antibiotic effectiveness against ESKAPE pathogens. The objective of this study was to data produced from identify microorganism with antibiotic potential.