Advances in MRI of Chronic Pancreatitis

Abstract

MRI and MRCP play an essential role in diagnosing CP by imaging pancreatic parenchyma and ducts. Quantitative and semi-quantitative MR imaging offers potential advantages over conventional MR imaging, including simplicity of analysis, quantitative and population-based comparisons, and more direct interpretation of disease progression or response to drug therapy. Using parenchymal imaging techniques may provide quantitative metrics for determining the presence and severity of acinar cell loss and aid in diagnosing CP. Given that the parenchymal changes of CP precede the ductal involvement, there would be a significant benefit from developing a new MRI/MRCP based, more robust diagnostic criteria combining ductal and parenchymal findings.