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Item The effects of remodeling with heart failure on mode of initiation of ventricular fibrillation and its spatiotemporal organization(Springer, 2015-09) Everett, Thomas H.; Hulley, George S.; Lee, Ken W.; Chang, Roger; Wilson, Emily E.; Olgin, Jeffrey E.; Department of Medicine, IU School of MedicinePurpose The effect of the heart failure substrate on the initiation of ventricular fibrillation (VF) and its resulting mechanism is not known. The objective of this study was to determine the effects of substrate on VF initiation and its spatiotemporal organization in the heart failure model. Methods Optical action potentials were recorded from LV wedge preparations either from structurally normal hearts (control, n = 11) or from congestive heart failure (CHF; n = 7), at the epicardial surface, endocardial surface which included a papillary muscle, and a transmural cross section. Action potential duration (APD80) was determined, and VF was initiated. A fast Fourier transform was calculated, and the dominant frequency (DF) was determined. Results The CHF group showed increased VF vulnerability (69 vs 26 %, p < 0.03), and every mapped surface showed an APD80 gradient which included islands of higher APDs on the transmural surface (M cells) which was not observed in controls. VF in the CHF group was characterized by stable, discrete, high-DF areas that correlated to either foci or spiral waves located on the transmural surface at the site of the papillary muscle. Overall, the top 10 % of DFs correlated to an APD of 101 ms while the bottom 10 % of DFs correlated to an APD of 126 ms (p < 0.01). Conclusions In the CHF model, APD gradients correlated with an increased vulnerability to VF, and the highest stable DFs were located on the transmural surface which was not seen in controls. This indicates that the CHF substrate creates unique APD and DF characteristics.Item Rule-Based Scan-to-BIM Mapping Pipeline in the Plumbing System(MDPI, 2020-11) Kang, Taewook; Patil, Shashidhar; Kang, Kyubyung; Koo, Dan; Kim, Jonghoon; Engineering Technology, School of Engineering and TechnologyThe number of scan-to-BIM projects that convert scanned data into Building Information Modeling (BIM) for facility management applications in the Mechanical, Electrical and Plumbing (MEP) fields has been increasing. This conversion features an application purpose-oriented process, so the Scan-to-BIM work parameters to be applied vary in each project. Inevitably, a modeler manually adjusts the BIM modeling parameters according to the application purpose, and repeats the Scan-to-BIM process until the desired result is achieved. This repetitive manual process has adverse consequences for project productivity and quality. If the Scan-to-BIM process can be formalized based on predefined rules, the repetitive process in various cases can be automated by re-adjusting only the parameters. In addition, the predefined rule-based Scan-to-BIM pipeline can be stored and reused as a library. This study proposes a rule-based Scan-to-BIM Mapping Pipeline to support application-oriented Scan-to-BIM process automation, variability and reusability. The application target of the proposed pipeline method is the plumbing system that occupies a large number of MEPs. The proposed method was implemented using an automatic generation algorithm, and its effectiveness was verified.Item Virtual Expeditions: Google Earth, GIS, and Geovisualization Technologies in Teaching and Learning(2010-02) Lamb, Annette; Johnson, Larry