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Item Multi-label natural language processing to identify diagnosis and procedure codes from MIMIC-III inpatient notes(arXiv, 2020) Bhavani Singh, A. K.; Guntu, Mounika; Bhimireddy, Ananth Reddy; Gichoya, Judy W.; Purkayastha, Saptarshi; BioHealth Informatics, School of Informatics and ComputingIn the United States, 25% or greater than 200 billion dollars of hospital spending accounts for administrative costs that involve services for medical coding and billing. With the increasing number of patient records, manual assignment of the codes performed is overwhelming, time-consuming and error-prone, causing billing errors. Natural language processing can automate the extraction of codes/labels from unstructured clinical notes, which can aid human coders to save time, increase productivity, and verify medical coding errors. Our objective is to identify appropriate diagnosis and procedure codes from clinical notes by performing multi-label classification. We used de-identified data of critical care patients from the MIMIC-III database and subset the data to select the ten (top-10) and fifty (top-50) most common diagnoses and procedures, which covers 47.45% and 74.12% of all admissions respectively. We implemented state-of-the-art Bidirectional Encoder Representations from Transformers (BERT) to fine-tune the language model on 80% of the data and validated on the remaining 20%. The model achieved an overall accuracy of 87.08%, an F1 score of 85.82%, and an AUC of 91.76% for top-10 codes. For the top-50 codes, our model achieved an overall accuracy of 93.76%, an F1 score of 92.24%, and AUC of 91%. When compared to previously published research, our model outperforms in predicting codes from the clinical text. We discuss approaches to generalize the knowledge discovery process of our MIMIC-BERT to other clinical notes. This can help human coders to save time, prevent backlogs, and additional costs due to coding errors.Item Natural language processing of MIMIC-III clinical notes for identifying diagnosis and procedures with neural networks(arXiv, 2019) Nuthakki, Siddhartha; Neela, Sunil; Gichoya, Judy W.; Purkayastha, Saptarshi; BioHealth Informatics, School of Informatics and ComputingCoding diagnosis and procedures in medical records is a crucial process in the healthcare industry, which includes the creation of accurate billings, receiving reimbursements from payers, and creating standardized patient care records. In the United States, Billing and Insurance related activities cost around $471 billion in 2012 which constitutes about 25% of all the U.S hospital spending. In this paper, we report the performance of a natural language processing model that can map clinical notes to medical codes, and predict final diagnosis from unstructured entries of history of present illness, symptoms at the time of admission, etc. Previous studies have demonstrated that deep learning models perform better at such mapping when compared to conventional machine learning models. Therefore, we employed state-of-the-art deep learning method, ULMFiT on the largest emergency department clinical notes dataset MIMIC III which has 1.2M clinical notes to select for the top-10 and top-50 diagnosis and procedure codes. Our models were able to predict the top-10 diagnoses and procedures with 80.3% and 80.5% accuracy, whereas the top-50 ICD-9 codes of diagnosis and procedures are predicted with 70.7% and 63.9% accuracy. Prediction of diagnosis and procedures from unstructured clinical notes benefit human coders to save time, eliminate errors and minimize costs. With promising scores from our present model, the next step would be to deploy this on a small-scale real-world scenario and compare it with human coders as the gold standard. We believe that further research of this approach can create highly accurate predictions that can ease the workflow in a clinical setting.