Browsing by Subject "aortic dissection"

Now showing 1 - 3 of 3
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    Aortic dissections in Marfan disease during pregnancy: Review article
    (Wiley, 2020-08) Cottrell, Jesse; Calhoun, John; Szczepanski, Jamie; Corvera, Joel; Cresswell, Lawrence; Kogon, Brian; Hasaniya, Nahidh; Copeland, Hannah; Surgery, School of Medicine
    We want to thank Dr. Raveenthiran and Dr. Harky for their interest in our paper and in the topic of Marfans in the setting of pregnancy. Certainly, the reduction of adverse outcomes would be improved with early knowledge of Marfans syndrome in the mother which would aid in preparation and clinical consideration during the perioperative period, and, prior to pregnancy.
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    A Case of Fatal Stanford Type A Aortic Dissection Caused by a Traffic Accident with Low Energy Impact
    (Dove Press, 2020-10-14) Mori, Shusuke; Ai, Tomohiko; Morishita, Koji; Otomo, Yasuhiro; Medicine, School of Medicine
    A seemingly healthy 84-year-old female pedestrian was mildly bumped by a car, and she hit her left shoulder, flank, and lower legs when she fell down on a street. She was conscious and stable when transferred to an emergency room. She had no sign of any major injuries except minor lacerations on her legs. Repeated evaluations including chest X-ray, ECG, and focused assessment with sonography for trauma did not reveal any abnormal findings. While waiting for discharge, she started having mild chest discomfort. Unexpectedly, the third echocardiogram showed mild pericardial effusion, and a CT with contrast showed aortic dissection in the ascending aorta and infra-left subclavian aortic dissection. She was immediately transferred by a helicopter to a tertiary trauma center for emergent repair surgery. Considering the site of dissections, progression of existing intrinsic intimal tear triggered by energy impact was suspected. However, traumatic causes could not be excluded. Extra caution and diligence should be exercised when examining elderly patients in blunt trauma.
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    Molecular and Genetic Insights into Thoracic Aortic Dilation in Conotruncal Heart Defects
    (Frontiers Media SA, 2016) Kay, W. Aaron; Department of Medicine, IU School of Medicine
    Thoracic aortic dilation (AD) has commonly been described in conotruncal defects (CTDs), such as tetralogy of Fallot, double outlet right ventricle and transposition of the great arteries, and truncus arteriosus. Several theories for this have been devised, but fairly recent data indicate that there is likely an underlying histologic abnormality, similar to that seen in Marfan and other connective tissue disease. The majority of aortic dissection in the general population occurs after the age of 45 years, and there have been very few case reports of aortic dissection in CTD. Given advances in cardiac surgery and increasing survival over the past several decades, there has been rising concern that, as patients who have survived surgical correction of these defects age, there may be increased morbidity and mortality due to aortic dissection and aortic regurgitation. This review discusses the most recent developments in research into AD in CTD, including associated genetic mutations.