Browsing by Author "Lieberman, Marya"

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    127 Reciprocal Innovation Workshops: Identify Shared Health Challenges for Mutual Benefit in Global Health
    (Cambridge University Press, 2022) Sors, Thomas; Wools-Kaloustian, Kara; O’Brien, Rishika Chauhan; Bermel, Luanne; Kiplagat, Jepchirchir; Lieberman, Marya; Morales-Soto, Nydia; Nyandiko, Winstone; Litzelman, Debra; Medicine, School of Medicine
    OBJECTIVES/GOALS: Our concept of reciprocal innovation (RI) supports global health (GH) research partnerships that address shared health challenges for mutual benefit in both high and low- and middle-income (LMIC) settings. To advance this GH approach, the Indiana CTSI launched a RI program building on longstanding global health partnerships in East Africa. METHODS/STUDY POPULATION: A core component of the program is annual RI workshops to promote reciprocal approaches in GH, identify priority areas for reciprocal research, and link investigators and stakeholders across settings. The first meeting in 2019 was in-person and focused on identifying health priority areas from the perspective of Indiana stakeholders. The second meeting was held virtually and focused on priority areas in East Africa. The third meeting focused on shared priority areas and discussing potential RI research projects. Agenda sessions include (1) presenting successful examples of funded RI projects; (2) breakout groups to share proposal ideas in preparation for the RI grants program; (3) building partnerships with colleagues in similar fields. RESULTS/ANTICIPATED RESULTS: As of 2021, three RI workshops have been held with an average of 60 attendees at each workshop. Participants identified several overlapping priority areas for research and RI in Indiana and East Africa, including research in chronic disease, substance abuse, infant and maternal health, and access to healthcare. A Global Health Innovation Exchange of RI projects was created to support connections between locally- and globally-focused investigators. The repository is used to share updates on project progress, outcomes, and published materials. Workshops have also been used to explore a reciprocal innovation virtual platform to facilitate and foster more regular collaborations between globally and locally-focused investigators and pursue research projects on shared health challenges for mutual benefit. DISCUSSION/SIGNIFICANCE: The collaboration at the stakeholder meetings set the foundation for continued partnership building, strong proposals for RI grants, and dissemination and translation of successful RI projects. To leverage momentum from the meetings, we are building a virtual RI platform to connect PIs across multiple CTSAs and increase the footprint of RI efforts
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    Ensuring Patient-Centered Access to Cardiovascular Disease Medicines in Low-Income and Middle-Income Countries Through Health-System Strengthening
    (Elsevier, 2017) Tran, Dan N.; Njuguna, Benson; Mercer, Timothy; Manji, Imran; Fischer, Lydia; Lieberman, Marya; Pastakia, Sonak; Medicine, School of Medicine
    Cardiovascular disease (CVD) is the leading cause of global mortality and is expected to reach 23 million deaths by 2030. 80% of CVD deaths occur in low- and middle- income countries (LMICs). Although CVD prevention and treatment guidelines are available, translating these into practice is hampered in LMICs by inadequate healthcare systems which limit access to lifesaving medications. In this review article, we describe the deficiencies in the current LMIC supply chains that limit access to effective CVD medicines, and discuss existing solutions that are translatable to similar settings in order to address these deficiencies.
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    Reciprocal innovation: A new approach to equitable and mutually beneficial global health partnerships
    (Taylor & Francis, 2023) Sors, Thomas G.; O’Brien, Rishika Chauhan; Scanlon, Michael L.; Bermel, Li Yuan; Chikowe, Ibrahim; Gardner, Adrian; Kiplagat, Jepchirchir; Lieberman, Marya; Moe, Sharon M.; Morales-Soto, Nydia; Nyandiko, Winstone M.; Plater, David; Rono, Betsy Cheriro; Tierney, William M.; Vreeman, Rachel C.; Wiehe, Sarah E.; Wools-Kaloustian, Kara; Litzelman, Debra K.; Medicine, School of Medicine
    Global health researchers often discount mutual learning and benefit to address shared health challenges across high and low- and middle-income settings. Drawing from a 30-year partnership called AMPATH that started between Indiana University in the US and Moi University in Kenya, we describe an innovative approach and program for mutual learning and benefit coined ‘reciprocal innovation.’ Reciprocal innovation harnesses a bidirectional, co-constituted, and iterative exchange of ideas, resources, and innovations to address shared health challenges across diverse global settings. The success of AMPATH in Kenya, particularly in HIV/AIDS and community health, resulted in several innovations being ‘brought back’ to the US. To promote the bidirectional flow of learning and innovations, the Indiana CTSI reciprocal innovation program hosts annual meetings of multinational researchers and practitioners to identify shared health challenges, support pilot grants for projects with reciprocal exchange and benefit, and produce educational materials to train investigators. The transformative power of global health to address systemic health inequities embraces equitable and reciprocal partnerships with mutual benefit across countries and communities of academics, practitioners, and policymakers. Leveraging a long-standing partnership, the Indiana CTSI has built a reciprocal innovation program with promise to redefine global health for shared wellbeing at a global scale.