Agrawal, VaibhavBrinda, Bryan J.Farag, Sherif S.2020-04-092020-04-092020-02-12Agrawal, V., Brinda, B. J., & Farag, S. S. (2020). Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis. Case reports in hematology, 2020, 8124137. https://doi.org/10.1155/2020/8124137https://hdl.handle.net/1805/22516Histoplasma capsulatum infection is a rare complication in the allogeneic stem cell transplant patients. Minimal guidance exists on how to appropriately manage histoplasmosis in these patients. We report a patient who developed Histoplasma pneumonia while receiving voriconazole prophylaxis at a therapeutic trough level. The patient experienced significant clinical improvement after initiation of itraconazole pharmacotherapy. We recommend a lower threshold for evaluation for histoplasmosis in allogeneic hematopoietic stem cell transplant recipients who live in endemic regions, regardless of their antifungal prophylactic regimen.en-USAttribution 4.0 InternationalHistoplasma capsulatumItraconazole pharmacotherapyAllogeneic hematopoietic stem cell transplantsEndemic regionsImmunocompromised patientsArticle