Starbuck, John MGhoneima, AhmedKula, Katherine2014-04-222015-04-232014-03-01Starbuck, J. M., Ghoneima, A., & Kula, K. (2014). Facial Soft-Tissue Asymmetry in Three-Dimensional Cone-Beam Computed Tomography Images of Children With Surgically Corrected Unilateral Clefts. Journal of Craniofacial Surgery, 25(2), 476-480.https://hdl.handle.net/1805/4297Cleft lip with or without cleft palate (CL/P) is a relatively common craniofacial malformation involving bony and soft-tissue disruptions of the nasolabial and dentoalveolar regions. The combination of CL/P and subsequent craniofacial surgeries to close the cleft and improve appearance of the cutaneous upper lip and nose can cause scarring and muscle pull, possibly resulting in soft-tissue depth asymmetries across the face. We tested the hypothesis that tissue depths in children with unilateral CL/P exhibit differences in symmetry across the sides of the face. Twenty-eight tissue depths were measured on cone-beam computed tomography images of children with unilateral CL/P (n = 55), aged 7 to 17 years, using Dolphin software (version 11.5). Significant differences in tissue depth symmetry were found around the cutaneous upper lip and nose in patients with unilateral CL/P.en-USsoft-tissue depthfacial reconstructioncleft lip with or without cleft palateArticle