Bungart, BrittaniCao, YingchunYang-Tran, TiffanyGorsky, SeanLan, LuRoblyer, DarrenKoch, Michael O.Cheng, LiangMasterson, TimothyCheng, Ji-Xin2019-09-052019-09-052019-02-22Bungart, B., Cao, Y., Yang-Tran, T., Gorsky, S., Lan, L., Roblyer, D., … Cheng, J. X. (2019). Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography. Biomedical optics express, 10(3), 1405–1419. doi:10.1364/BOE.10.001405https://hdl.handle.net/1805/20818Current diagnosis of prostate cancer relies on histological analysis of tissue samples acquired by biopsy, which could benefit from real-time identification of suspicious lesions. Photoacoustic tomography has the potential to provide real-time targets for prostate biopsy guidance with chemical selectivity, but light delivered from the rectal cavity has been unable to penetrate to the anterior prostate. To overcome this barrier, a urethral device with cylindrical illumination is developed for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostate-mimicking phantom.en-USPublisher PolicyProstate cancerPhotoacoustic tomographyReal-time targetsProstate biopsy guidanceUrethral deviceCylindrical illuminationWhole-prostate imagingAngular light couplingArticle