Needleman, Joseph S.Hanson, Amy E.2020-08-192020-08-192020-08-12Needleman, J. S., & Hanson, A. E. (2020). COVID-19-associated apnea and circumoral cyanosis in a 3-week-old. BMC Pediatrics, 20. https://doi.org/10.1186/s12887-020-02282-81471-2431https://hdl.handle.net/1805/23636Background: Data regarding coronavirus disease 2019 (COVID-19) cases and outcomes in infants are sparse compared to older pediatric and adult populations. Case presentation: We present a three-week-old full-term male with a history of mild hypoxic ischemic encephalopathy (HIE) who was admitted as an inpatient twice for episodes of apnea and perioral cyanosis. The patient tested positive for COVID-19 and negative for other common respiratory viruses at both admissions. Conclusions: To our knowledge, this is the first report of apnea and perioral cyanosis associated with COVID-19 in an infant. This case highlights a previously undocumented COVID-19 presentation and suggests that even mildly symptomatic infants warrant viral diagnostic testing in an effort to prevent further spread of the disease.en-USAttribution 4.0 InternationalCOVID-19ApneaCircumoral CyanosisInfantCase StudyArticle