Parker, Maria A.Ichikawa, Jodi K.Bombardier, Charles H.Hammond, Flora M.2023-08-302023-08-302022-08-03Parker MA, Ichikawa JK, Bombardier CH, Hammond FM. Association Between Anxiety Symptoms, Depression Symptoms, and Life Satisfaction Among Individuals 1 Year After Spinal Cord Injury: Findings From the SCIRehab Project. Arch Rehabil Res Clin Transl. 2022;4(3):100211. Published 2022 Aug 3. doi:10.1016/j.arrct.2022.100211https://hdl.handle.net/1805/35237Objective: To examine the association between anxiety symptoms, depression symptoms, and life satisfaction 1 year after SCI. Design: Cross-sectional analysis of data from the SCIRehab Project. A linear regression model estimated the association between anxiety symptoms and life satisfaction and tested the moderating effect of depression symptoms on the association between anxiety symptoms and depression symptoms with an interaction term. Setting: Six rehabilitation facilities across the United States. Participants: A total to 940 persons older than 12 years who received inpatient spinal cord injury (SCI) rehabilitation between 2007 and 2009 were followed up 1 year post injury (n=940). Interventions: None. Main outcome measures: Life satisfaction 1 year after SCI measured via the Satisfaction With Life Scale. Results: Unadjusted analyses showed anxiety symptoms were associated with decreased life satisfaction for individuals with SCI. In adjusted analyses, anxiety symptoms were not associated with life satisfaction. In adding an interaction term, anxiety symptoms were associated with 2 points lower life satisfaction holding the other variables constant (P=.02). There was a moderating effect of depression symptoms on the association between anxiety symptoms and life satisfaction. Persons with anxiety symptoms had lower life satisfaction scores at lower levels of depression symptoms but higher life satisfaction scores at higher levels of depression symptoms than persons with no anxiety. Conclusions: In clinical settings, both anxiety and depression symptoms should be monitored, measured, and treated together to optimally improve life satisfaction for persons with SCI. Prioritizing interventions known to have transdiagnostic effects may achieve the best results.en-USAttribution-NonCommercial-NoDerivatives 4.0 InternationalAmerican Spinal Injury Association Impairment ScaleAnxietyDepressionGeneralized Anxiety DisorderPatient Health QuestionnairePersonal satisfactionRehabilitationSpinal cord injuryArticle