Lewis, Katherine A.Goldyn, Andrea K.West, Karen W.Eugster, Erica A.2025-05-062025-05-062013Lewis KA, Goldyn AK, West KW, Eugster EA. A single histrelin implant is effective for 2 years for treatment of central precocious puberty. J Pediatr. 2013;163(4):1214-1216. doi:10.1016/j.jpeds.2013.05.033https://hdl.handle.net/1805/47785We investigated whether a "yearly" histrelin implant would provide pubertal suppression when left in place for 2 years. Equivalent suppression was observed when comparing 12 and 24 months in 33 children with central precocious puberty. A single implant for 2 years reduces cost and number of implant procedures.en-USPublisher PolicyCentral precocious pubertyGonadotropin releasing hormone analogHypothalamic-pituitary-gonadalLuteinizing hormoneUltrasensitiveArticle