Salfity, HaiTimsina, LavaSu, KatherineCeppa, DuyKhanhBirdas, Thomas2019-09-092019-09-092019Salfity, H., Timsina, L., Su, K., Ceppa, D., & Birdas, T. (2019). Case Volume-to-Outcome Relationship in Minimally-Invasive Esophagogastrectomy. The Annals of Thoracic Surgery. https://doi.org/10.1016/j.athoracsur.2019.05.054https://hdl.handle.net/1805/20885Background Outcomes after open esophagectomy (OE) have been shown to depend on institution case volume. We aim to determine whether a similar relationship exists for minimally-invasive esophagogastrectomy (MIE). Methods Patients who had OE or MIE (excluding robotic procdures) between 2010 and 2013 in the National Cancer Database were included. Outcomes included 30- and 90-day mortality, length-of-stay, hospital readmission, margin positivity, and number of lymph nodes harvested. Logistic and linear regression were used to adjust for possible confounders including age, gender, tumor size, Charlson score, induction therapy, and type of institution (academic vs. community-based). Results We identified 2371 patients in the MIE group and 6285 patients in the OE group. In multivariate analysis, high case volume was an independent predictor for lower 30-day, 90-day mortality, shorter length-of-stay, and higher rate of negative-margin resection in OE (P<0.001) but not MIE. After quartile ranking of institutions based on volume, MIE outcomes were found to be better in institutions in the highest volume quartile compared to those in the lowest (p< 0.0001). Conclusions In this dataset, MIE postoperative outcomes, unlike OE, did not correlate with hospital case volume. Volume-outcome relationships may be affected by surgical approach. The effect of case volume on long-term outcomes after MIE warrants further study.enPublisher Policyopen esophagectomyminimally-invasive esophagogastrectomyhospital case volumeArticle