Singh, NareshSharma, Samantha2024-09-162024-09-162024Singh N, Sharma S. Photo-activated microtubule targeting drugs: Advancing therapies for colorectal cancer. World J Gastroenterol. 2024;30(26):3257-3260. doi:10.3748/wjg.v30.i26.3257https://hdl.handle.net/1805/43325Over the years immunotherapy has demonstrably improved the field of cancer treatment. However, achieving long-term survival for colorectal cancer (CRC) patients remains a significant unmet need. Combination immunotherapies incorporating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit. Nevertheless, substantial gaps remain in the current therapeutic armamentarium for CRC. In recent years, there has been a surge of interest in exploring novel treatment strategies, including the application of light-activated drugs in conjunction with optical devices. This approach holds promise for achieving localized and targeted delivery of cytotoxic agents, such as microtubule-targeting drugs, directly to cancerous cells within the colon.en-USAttribution-NonCommercial 4.0 InternationalColorectal cancerTherapyMicrotubulePhoto pharmacologyImmunotherapiesArticle