Castravete, ŞtefanMazilu, DumitruGruionu, Lucian GheorgheMilitaru, CristianMilitaru, SebastianUdriŞtoiu, Anca-LoredanaIacob, Andreea ValentinaGruionu, Gabriel2022-04-202022-04-202020-09-30Castravete Ş, Mazilu D, Gruionu LG, Militaru C, Militaru S, UdriŞtoiu AL, Iacob AV, Gruionu G. Finite Element Analysis of a Novel Aortic Valve Stent. Curr Health Sci J. 2020 Jul-Sep;46(3):290-296. doi: 10.12865/CHSJ.46.03.11. Epub 2020 Sep 30. PMID: 33304631; PMCID: PMC7716760.https://hdl.handle.net/1805/28608Worldwide, one of the leading causes of death for patients with cardiovascular disease is aortic valve failure or insufficiency as a result of calcification and cardiovascular disease. The surgical treatment consists of repair or total replacement of the aortic valve. Artificial aortic valve implantation via a percutaneous or endovascular procedure is the minimally invasive alternative to open chest surgery, and the only option for high-risk or older patients. Due to the complex anatomical location between the left ventricle and the aorta, there are still engineering design optimization challenges which influence the long-term durability of the valve. In this study we developed a computer model and performed a numerical analysis of an original self-expanding stent for transcatheter aortic valve in order to optimize its design and materials. The study demonstrates the current valve design could be a good alternative to the existing commercially available valve devices.en-USAttribution-NonCommercial-ShareAlike 4.0 InternationalAortic valveStentFinite elementsNitinolArticle