Wood, AnthonyAdra, NabilCheng, LiangPili, Roberto2017-06-212017-06-212017-03Wood A., Adra N., Cheng L., Pili R. (2017). Metastatic small cell carcinoma of the prostate in an octogenarian with significant response to first-line chemotherapy. Hematol Med Oncol 2: DOI: 10.15761/HMO.1000120https://hdl.handle.net/1805/13140Patients with small cell carcinoma of the prostate generally present with metastatic disease and have an estimated life expectancy measured in months. In this brief report, we present a case of rapidly progressive metastatic small cell carcinoma of the prostate in an octogenarian with significant response to split-dosed cisplatin and etoposide. This case report shows that cautious treatment with platinum-based regimens should still be considered in elderly patients given the potential for improvement in performance status and quality of life with chemotherapy. Additionally, this case highlights that platinum-based regimens are still considered the therapeutic backbone of prostate cancers with a mixed small cell carcinoma and adenocarcinoma phenotype.ensmall cell carcinomaprostatechemotherapyArticle