Bottino, Marco C.Pankajakshan, DivyaNör, Jacques E.2019-05-132019-05-132017-10Bottino, M. C., Pankajakshan, D., & Nör, J. E. (2017). Advanced Scaffolds for Dental Pulp and Periodontal Regeneration. Dental clinics of North America, 61(4), 689–711. doi:10.1016/j.cden.2017.06.009https://hdl.handle.net/1805/19270No current therapy promotes root canal disinfection and regeneration of the pulp-dentin complex in cases of pulp necrosis. Antibiotic pastes used to eradicate canal infection negatively affect stem cell survival. Three-dimensional easy-to-fit antibiotic-eluting nanofibers, combined with injectable scaffolds, enriched or not with stem cells and/or growth factors, may increase the likelihood of achieving predictable dental pulp regeneration. Periodontitis is an aggressive disease that impairs the integrity of tooth-supporting structures and may lead to tooth loss. The latest advances in membrane biomodification to endow needed functionalities and technologies to engineer patient-specific membranes/constructs to amplify periodontal regeneration are presented.en-USPublisher Policy3D printingBiomaterialsDental pulpGuided tissue regenerationPeriodontitisPulpitisRegenerative endodonticsScaffoldsArticle