Danner, AnaHays, MatthewLi, YangJohns, Shelley2025-09-232025-09-232025-04-05Danner, A., Hays, M., Li, Y., Johns, S. (5 April 2025). Suffering in Silence: A Mixed Methods Analysis Exploring the Relationship Between Clinically Significant Distress and Mental Health Service Use in Breast Cancer Survivors. American College of Physicians 2025 National Internal Medicine Meeting. New Orleans, LA. (Poster Presentation; Medical Student Clinical Research Category).https://hdl.handle.net/1805/51216Introduction: Breast cancer survivors (BCS) have an increased risk of psychological distress, including symptoms of depression, anxiety, and post-traumatic stress, compared to healthy controls. Fear of cancer recurrence (FCR) is an especially prevalent form of distress, with approximately 50% of BCS reporting clinically significant FCR. This mixed-methods study explored relationships between psychological distress, mental health service (MHS) use, and barriers to MHS use among BCS. Methods: Baseline data from 384 early-stage, post-treatment BCS with clinically significant FCR at screening enrolled in a randomized controlled trial comparing 3 FCR interventions were analyzed. The prevalence of clinically significant FCR, anxiety, depression, and post-traumatic stress symptoms was measured. Associations between distress measures and MHS use were assessed. Qualitative interviews were conducted with 24 distressed BCS to elucidate barriers hindering their use of MHS. Results: Clinically significant levels of at least one form of distress besides FCR were reported in 226 (58.85%) BCS. Of 298 (77.60%) BCS with at least one significant distress score including FCR, only 61 (20.47%) reported using any MHS within the 3 months before baseline. Clinically significant anxiety (p = 0.0027), depression (p = 0.0015), and post-traumatic stress symptoms (p = 0.0227) were significantly associated with MHS use. Conversely, FCR was significantly associated with fewer visits to certain MHS. Qualitative interviews revealed personal and systemic barriers contributing to underutilization of MHS in BCS, including avoidant coping, financial constraints, inaccessibility to providers speaking the survivor’s first language, and limited timely care options. Conclusion: Only a minority of clinically distressed BCS use MHS. Anxiety, depression, and post-traumatic stress symptoms may be better predictors of MHS use than FCR given the tendency for fearful survivors to cope with avoidance. Interventions emphasizing alternatives to avoidant coping may benefit BCS with FCR. Further research is needed to identify solutions to the multifaceted barriers impeding MHS use among BCS.en-USacceptance and commitment therapybreast cancercancer survivorshipfearmental health servicesmixed methods studypsychological distressoncologyPoster