Guest, James D.Luo, ZhuojingLiu, YanshengGao, HongkunWang, DianchunXu, Xiao-MingZhu, Hui2024-02-132024-02-132023Guest JD, Luo Z, Liu Y, et al. Acute penetrating injury of the spinal cord by a wooden spike with delayed surgery: a case report. Neural Regen Res. 2023;18(12):2781-2784. doi:10.4103/1673-5374.373668https://hdl.handle.net/1805/38455Rarely, penetrating injuries to the spinal cord result from wooden objects, creating unique challenges to mitigate neurological injury and high rates of infection and foreign body reactions. We report a man who sustained a penetrating cervical spinal cord injury from a sharpened stick. While initially tetraparetic, he rapidly recovered function. The risks of neurological deterioration during surgical removal made the patient reluctant to consent to surgery despite the impalement of the spinal cord. A repeat MRI on day 3 showed an extension of edema indicating progressive inflammation. On the 7th day after injury, fever and paresthesias occurred with a large increase in serum inflammatory indicators, and the patient agreed to undergo surgical removal of the wooden object. We discuss the management nuances related to wood, the longitudinal evolution of MRI findings, infection risk, surgical risk mitigation and technique, an inflammatory marker profile, long-term recovery, and the surprisingly minimal neurological deficits associated with low-velocity midline spinal cord injuries. The patient had an excellent clinical outcome. The main lessons are that a wooden penetrating central nervous system injury has a high risk for infection, and that surgical removal from the spinal cord should be performed soon after injury and under direct visualization.en-USAttribution-NonCommercial-ShareAlike 4.0 InternationalCase reportInterleukin-6Magnetic resonance imagingPenetratingSpinal cord injuryWoodArticle