Lee, HyungjunYuan, YueRhee, InmooCorson, Timothy W.Seo, Seung-Yong2017-05-262017-05-262016-08Lee H, Yuan Y, Rhee I, Corson TW, Seo SY. 2016. Synthesis of natural homoisoflavonoids having either 5,7-dihydroxy-6-methoxy or 7-hydroxy-5,6-dimethoxy groups. Molecules, 21, 1058. http://dx.doi.org/10.3390/molecules21081058https://hdl.handle.net/1805/12750Naturally occurring homoisoflavonoids containing either 5,7-dihydroxy-6-methoxy or 7-hydroxy-5,6-dimethoxy groups such as the antiangiogenic homoisoflavanone, cremastranone, were synthesized via three or four linear steps from the known 4-chromenone. This facile synthesis includes chemoselective 1,4-reduction of 4-chromenone and selective deprotection of 3-benzylidene-4-chromanone a containing C7-benzyloxy group.enAttribution 3.0 United Stateshomoisoflavonoidscremastranone4-chromanoneArticle