Griesenauer, BradPaczesny, Sophie2019-05-232019-05-232018-06-04Griesenauer, B., & Paczesny, S. (2018). Less cholesterol means better tumor killing for cytotoxic T9 cells. The Journal of experimental medicine, 215(6), 1505–1506. doi:10.1084/jem.20180852https://hdl.handle.net/1805/19452In this issue, Ma et al. (https://doi.org/10.1084/jem.20171576) show that removal of cholesterol from CD8 T cells during type 9 differentiation increases their IL-9 production, persistence in vivo, and cytolytic function against tumors by preventing SUMOylation of liver X receptors.en-USAttribution-NonCommercial-NoDerivs 3.0 United StatesCholesterolCD8 T cellsType 9 differentiationIL-9 productionLiver X receptorsArticle