Bai, ZengdingZhu, Luoding2019-11-212019-11-212019-03Bai, Z., & Zhu, L. (2019). 3D simulation of a viscous flow past a compliant model of arteriovenous-graft annastomosis. Computers & Fluids, 181, 403–415. https://doi.org/10.1016/j.compfluid.2019.02.006https://hdl.handle.net/1805/21369Hemodialysis is a common treatment for end-stage renal-disease patients to manage their renal failure while awaiting kidney transplant. Arteriovenous graft (AVG) is a major vascular access for hemodialysis but often fails due to the thrombosis near the vein-graft anastomosis. Almost all of the existing computational studies involving AVG assume that the vein and graft are rigid. As a first step to include vein/graft flexibility, we consider an ideal vein-AVG anastomosis model and apply the lattice Boltzmann-immersed boundary (LB-IB) framework for fluid-structure-interaction. The framework is extended to the case of non-uniform Lagrangian mesh for complex structure. After verification and validation of the numerical method and its implementation, many simulations are performed to simulate a viscous incompressible flow past the anastomosis model under pulsatile flow condition using various levels of vein elasticity. Our simulation results indicate that vein compliance may lessen flow disturbance and a more compliant vein experiences less wall shear stress (WSS).enAttribution 3.0 United Statesarteriovenous graftblood flowhemodialysisArticle