Zhong, XiaolinHuang, MenghaoKim, Hyeong-GeugZhang, YangChowdhury, KushanCai, WenjieSaxena, RomilSchwabe, Robert F.Liangpunsakul, SuthatDong, X. Charlie2020-11-182020-11-182020-04-17Zhong, X., Huang, M., Kim, H.-G., Zhang, Y., Chowdhury, K., Cai, W., Saxena, R., Schwabe, R. F., Liangpunsakul, S., & Dong, X. C. (2020). SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells. Cellular and Molecular Gastroenterology and Hepatology, 10(2), 341–364. https://doi.org/10.1016/j.jcmgh.2020.04.0052352-345Xhttps://hdl.handle.net/1805/24446en-USAttribution-NonCommercial-NoDerivatives 4.0 Internationalalanine aminotransferasechromatin immunoprecipitationDulbecco’s modified Eagle mediumgreen fluorescent proteinhemagglutininhepatic stellate cellKO knockoutLratlecithin retinol acyltransferasemRNA messengerNAFLD nonalcoholic fatty liver diseaseNASH nonalcoholic steatohepatitisPBS phosphate-buffered salinePCR polymerase chain reactionshRNA short hairpin RNASIRT6 sirtuin 6SMAD3 SMAD family member 3transgenictransforming growth factor βWestern dietwild-typeArticle