Gavin, WarrenCampbell, ElliottZaidi, AdeelGavin, NehaDbeibo, LanaBeeler, ColeKuebler, KariAbdel-Rahman, AhmedLuetkemeyer, MarkKara, Areeba2020-07-212020-07-212020-07-08Gavin, W., Campbell, E., Zaidi, A., Gavin, N., Dbeibo, L., Beeler, C., Kuebler, K., Abdel-Rahman, A., Luetkemeyer, M., & Kara, A. (2020). “Clinical Characteristics, Outcomes and Prognosticators in Adult Patients Hospitalized with COVID-19.” American Journal of Infection Control. https://doi.org/10.1016/j.ajic.2020.07.0050196-6553https://hdl.handle.net/1805/23287Background: COVID-19 is a novel disease caused by SARS-CoV-2. Methods: We conducted a retrospective evaluation of patients admitted with COVID-19 to one site in March 2020. Patients were stratified into three groups: survivors who did not receive mechanical ventilation (MV), survivors who received MV and those who received MV and died during hospitalization. Results: There were 140 hospitalizations; 22 deaths (mortality rate 15.7%), 83 (59%) survived and did not receive MV, 35 (25%) received MV and survived; 18 (12.9%) received MV and died. Thee mean age of each group was 57.8 , 55.8 and 72.7 years respectively (p=.0001). Of those who received MV and died, 61% were male (p=.01). More than half the patients ( n=90, 64%) were African American. First measured d-dimer >575.5 ng/mL, procalcitonin > 0.24 ng/mL, LDH > 445.6 units/L and BNP > 104.75 pg/mL had odds ratios of 10.5, 5 , 4.5 and 2.9 respectively forMV (p < .05 for all). Peak BNP > 167.5 pg/mL had an odds ratio of 6.7 for inpatient mortalitywhen mechanically ventilated (p= .02).Conclusions: Age and gender may impact outcomes in COVID-19. D-dimer, procalcitonin, LDH and BNP may serve as early indicators of disease trajectory.en-USIUPUI Open Access PolicyCOVID-19AdultsHospitalizationsMechanical VentilationHealth DisparitiesMorbiditiesArticle