Chen, ChengxuanHan, Leng2025-05-132025-05-132025Chen C, Han L. Deciphering genetic regulation at single-cell resolution in gastric cancer. Cell Genom. 2025;5(4):100846. doi:10.1016/j.xgen.2025.100846https://hdl.handle.net/1805/48030Understanding cell-type-specific genetic regulation in gastric cancer is essential for uncovering disease susceptibility. By performing single-cell eQTL mapping in gastric tissues, Bian et al.1 identified previously uncharacterized regulatory genetic mechanisms, risk genes, and co-localization signals associated with gastric cancer susceptibility, providing insights into its pathogenesis and potential therapeutic approaches.en-USAttribution-NonCommercial 4.0 InternationalGenetic predisposition to diseaseQuantitative trait lociSingle-cell analysisStomach neoplasmsArticle