Pavelka, Matthew M.Kohr, Roland2025-02-182025-02-182024-01-30Pavelka MM, Kohr R. Potential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide. Acad Forensic Pathol. 2024;14(1):21-25. Published 2024 Jan 30. doi:10.1177/19253621231224531https://hdl.handle.net/1805/45789Limited case reports have been published regarding serotonin syndrome due to the combined effects of supratherapeutic levels of dextromethorphan and selective serotonin reuptake inhibitor. We report a case of an adolescent with postmortem findings suggestive of a diagnosis of serotonin syndrome-induced psychosis associated with a double homicide and suicide. Postmortem toxicology of the suicide victim was remarkable for elevated serotonergic metabolites of fluoxetine and dextromethorphan in a 14-year-old male.en-USPublisher PolicyDextromethorphanFluoxetineForensic pathologySerotonin syndromeArticle