Hafezi, NiloufarPecoraro, AnthonyLandman, Matthew P.Colgate, CameronRescorla, Frederick J.2023-03-242023-03-242021-11Hafezi N, Pecoraro A, Landman MP, Colgate C, Rescorla FJ. Pediatric Complicated Appendicitis During the COVID-19 Pandemic: A National Perspective. J Am Coll Surg. 2021;233(5):S181. doi:10.1016/j.jamcollsurg.2021.07.364https://hdl.handle.net/1805/32058This article is made available for unrestricted research re-use and secondary analysis in any form or be any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemicIntroduction: The COVID-19 pandemic has changed the public’s perception of safety in accessing healthcare across common surgical emergencies, including acute appendicitis in children. Here, we aim to determine whether the COVID-19 pandemic is associated with poorer appendicitis outcomes and predict that there are higher complicated appendicitis (CA) rates during this time. Methods: A retrospective cohort study was conducted in patients younger than 19 years with a new diagnosis of acute appendicitis. Rates of CA were compared in the pre- (3/1/2019-5/31/2019) and post-COVID (3/1/2020-5/31/2020) timeframes using the Pediatric Health Information System national database. The primary end point of interest was CA rates. Secondary end point of interest was hospital length of stay. A p value < 0.05 was significant. Results: Nationally, 6,212 patients had acute appendicitis pre-COVID compared with 5,372 post-COVID. The CA rate post-COVID was 33%, which was significantly higher than 30% CA rate pre-COVID, and the rate of uncomplicated appendicitis post-COVID was lower (p < 0.001). An overall increase in hospital length of stay nationally was observed for all patients treated post-COVID (p < 0.001), as well as in those with CA (p < 0.001). Conclusion: The COVID-19 pandemic is directly associated with higher disease burden in pediatric acute appendicitis. The healthcare system must understand its role in alleviating public fear in seeking healthcare for patients and their families to encourage timely medical care.en-USPublic Health EmergencyCOVID-19 pandemicTreatment delaysPublic fearPediatric acute appendicitisArticle