Lory, CatharineKadlaskar, GirijaMcNally Keehn, RebeccaFrancis, Alexander L.Keehn, Brandon2023-04-062023-04-062020-11Lory C, Kadlaskar G, McNally Keehn R, Francis AL, Keehn B. Brief Report: Reduced Heart Rate Variability in Children with Autism Spectrum Disorder. J Autism Dev Disord. 2020;50(11):4183-4190. doi:10.1007/s10803-020-04458-8https://hdl.handle.net/1805/32264Dysregulation of the autonomic nervous system (ANS), which can be indexed by heart rate variability (HRV), has been posited to contribute to core features of autism spectrum disorder (ASD). However, the relationship between ASD and HRV remains uncertain. We assessed tonic and phasic HRV of 21 children with ASD and 21 age- and IQ-matched typically developing (TD) children and examined (1) group differences in HRV and (2) associations between HRV and ASD symptomatology. Children with ASD showed significantly lower tonic HRV, but similar phasic HRV compared to TD children. Additionally, reduced tonic HRV was associated with atypical attentional responsivity in ASD. Our findings suggest ANS dysregulation is present in ASD and may contribute to atypical attentional responses to sensory stimulation.en-USPublisher PolicyAutism spectrum disorderHeart rate variabilityECGAutonomic arousalArticle