Nikolitch, KaterinaSaraf, GayatriSolmi, MarcoKroenke, KurtFiedorowicz, Jess2025-04-112025-04-112023Nikolitch K, Saraf G, Solmi M, Kroenke K, Fiedorowicz JG. Fire and Darkness: On the Assessment and Management of Bipolar Disorder. Med Clin North Am. 2023;107(1):31-60. doi:10.1016/j.mcna.2022.04.002https://hdl.handle.net/1805/46967Bipolar disorder is characterized by recurrent mood episodes, affecting 1% to 2% of the population. Although its defining features are manic and hypomanic episodes, its course is dominated by depressive syndromes. Diagnosis can be challenging owing to symptom overlap with other disorders. Management goals include early and complete remission of acute episodes and the prevention of relapse between episodes. We present an overview of bipolar disorder and its subtypes, including algorithms and suggestions for screening, assessment, and treatment.en-USPublisher PolicyBipolar disorderDiagnosisPrimary carePsychopharmacologyTreatmentArticle