Hyslop, AlanWeller, Robert2024-10-292024-10-292024-09-15Hyslop A, Weller R. A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor. Respir Med Case Rep. 2024;52:102111. Published 2024 Sep 15. doi:10.1016/j.rmcr.2024.102111https://hdl.handle.net/1805/44288Central airway obstruction (CAO) is generally defined as airflow limitation due to >50 % occlusion and is most commonly due to malignant etiologies. However, benign etiologies, including herpes-simplex-virus (HSV) endobronchial pseudotumor, can occur. Due to the rarity of HSV causing airway obstruction, an evidence-based approach to the bronchoscopic resection and standardization of therapy after removal are lacking. Herein, we present a case of HSV pseudotumor successfully managed by argon-plasma-coagulation (APC) debulking via bronchoscopy and medical management with intravenous foscarnet due to failed treatment with acyclovir for previous HSV lesions.en-USAttribution-NonCommercial 4.0 InternationalCentral airway obstruction (CAO)Herpes-simplex-virus (HSV) pseudotumorArgon plasma coagulation (APC)Human immunodeficiency virus (HIV)Article