Pandya, Pankita H.Murrary, Mary E.Pollok, Karen E.Renbarger, Jamie L.2017-05-032017-05-032016-12-26Pandya, P. H., Murray, M. E., Pollok, K. E., & Renbarger, J. L. (2016). The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches. Journal of Immunology Research, 2016, 4273943. http://doi.org/10.1155/2016/4273943https://hdl.handle.net/1805/12437Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies.en-USAttribution-NonCommercial-NoDerivs 3.0 United StatesImmune activationCancer pathogenesisImmunooncologyCancer resistanceArticle